Results 131 to 140 of about 32,259 (328)

Impact of genotype–phenotype associations on prognosis in dilated cardiomyopathy

European Journal of Heart Failure, EarlyView.
Prediction of clinical outcomes in genetic dilated cardiomyopathy (DCM). LVEF, left ventricular ejection fraction. Aims Dilated cardiomyopathy (DCM) has a monogenic aetiology in up to 40% of patients. Understanding the spectrum of genotype–phenotype associations in DCM is crucial for risk stratification and personalized treatment.
Sophie L.V.M. Stroeks, Ping Wang, Marco Merlo, Steven Muller, Alessia Paldino, Nerea Mora‐Ayestaran, Max Jason, Matteo dal Ferro, Carola Pio Loco detto Gava, Fernando Dominguez, Esther Gonzalez‐Lopez, Arthur van den Wijngaard, Max F.G.H.M. Venner, Maurits Sikking, Michiel Minten, Bastien Nihant, Nina Beelen, Sharon Graw, Kristen Medo, Bart de Koning, Matthew Taylor, J. Peter van Tintelen, Luisa Mestroni, Gianfranco Sinagra, Anneline S.J.M. te Riele, Pablo Garcia‐Pavia, Stephane Heymans, Job A.J. Verdonschot   +27 more
wiley   +1 more source

The Use of Telemetry Monitoring Among General Medicine Patients [PDF]

, 2017
Objective: To determine why and when general medicine non-ICU patients are upgraded from a non-telemetry level of care to telemetry monitoring at Thomas Jefferson University Hospital (TJUH).
Chen, MD, Debbie, Diemer, MD, Gretchen A.   +1 more
core   +1 more source

Seizures and electroencephalographic findings in inborn errors of metabolism: Clues to differential diagnosis in the neonatal period, infancy, childhood and adolescence, and review of the literature

Epileptic Disorders, EarlyView.
Abstract Although inborn errors of metabolism (IEM) are a rare cause of epilepsy, seizures are a common presentation in these disorders. Seizures in IEM are frequently refractory to conventional anti‐seizure medication and might warrant initiation of specific treatments based on vitamins or dietary modifications or provision of alternative substrates ...
D. Kapoor, S. Sharma, A. Kaminska, R. Nabbout, N. Chemaly, M. Schiff, P. De Lonlay, M. Eisermann   +7 more
wiley   +1 more source

Frequency Analysis of Atrial Fibrillation From the Surface Electrocardiogram [PDF]

, 2004
Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice. Neither the natural history of AF nor its response to therapy are sufficiently predictable by clinical and echocardiographic parameters.
Bollmann, Andreas, Husser, Daniela, Olsson, Bertil, Sornmo, Leif, Stridh, Martin   +4 more
core  

A statistical technique for measuring synchronism between cortical regions in the EEG during rhythmic stimulation

, 2001
The coherence function has been widely applied in quantifying the degree of synchronism between electroencephalogram (EEG) signals obtained from different brain regions.
Infantosi, A.F.C., Miranda de Sa, A.M.F.L., Simpson, D.M.   +2 more
core   +1 more source

Integrative Evidence From Metabolome‐Wide Mendelian Randomization and Animal Models Implicates Tyrosine in Cardiac Hypercontractility and Arrhythmia Risk

Food Frontiers, EarlyView.
Plasma metabolome‐wide Mendelian randomization analysis established a causal link between tyrosine and arrhythmia. GWAS meta‐analysis identified tyrosine‐associated loci linked to cardiovascular risk factors. Animal studies confirmed that oral tyrosine intake modulates heart rhythm via adrenergic signaling activation.
Zhikang Cao, Huiying Liu, Peng Chen, Liyue Chen, Zhixin Chen, Jiaqiang Lin, Zixuan Fu, Zhipeng Li   +7 more
wiley   +1 more source

New insights into applications of base editor in hereditary disorders

Interdisciplinary Medicine, EarlyView.
Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai, Linhui Zhang, Liqing Li, Yue Liu, Canbin Lv, Yan Shi, Jianyuan Zhao, Dingwei Ye, Yuanyuan Qu   +8 more
wiley   +1 more source

Relation of symptoms and symptom duration to premature ventricular complex–induced cardiomyopathy [PDF]

, 2011
Miki Yokokawa, Hyungjin Myra Kim, Eric Good, Aman Chugh, Frank Pelosi, Craig T. Alguire, William F. Armstrong, Thomas Crawford, Krit Jongnarangsin, Hakan Oral, Fred Morady, Frank Bogun   +11 more
openalex   +1 more source

Prominent Chiari Network as a Cause of Cyanosis in Infants: A Case Report and Implications for Pediatric Cardiology Practice

Journal of Clinical Ultrasound, EarlyView.
A prominent Chiari network can cause cyanosis in infants by inducing a positional right‐to‐left atrial shunt. Accurate diagnosis enabled conservative management, delaying surgery until optimal conditions. This case emphasizes the importance of echocardiographic evaluation in differentiating cyanosis mechanisms to guide appropriate treatment in ...
Carmen Rodríguez‐Barrios, Irene Gutierrez‐Rosa, Moises Rodriguez‐Gonzalez   +2 more
wiley   +1 more source

Most costly and prevalent reasons for hospitalization in children with medical complexity in Ontario, Canada

Journal of Hospital Medicine, EarlyView.
Abstract Background and Objectives Children with medical complexity (CMC) have chronic health conditions often associated with functional limitations. CMC comprise 1%–5% of the pediatric population. In Canada, their care accounts for one‐third of pediatric health spending.
Erin Hessey, Thaksha Thavam, Sanjay Mahant, Eyal Cohen, Jingqin Zhu, Francine Buchanan, Teresa To, Peter J. Gill, Ontario Pediatric Hospital Care Study Group (OPHCSG) and the Canadian Paediatric Inpatient Research Network (PIRN), Wenjia Chen, Ronald Cohn, Mairead Green, Matt Hall, Kate Langrish, Colin Macarthur, Myla Moretti, Patricia Parkin, Michelle Quinlan, Ann Bayliss, Ronik Kanani, Sean Murray, Catherine Pound, Mahmoud Sakran, Anupam Sehgal, Sepi Taheri, Gita Wahi   +25 more
wiley   +1 more source