Results 71 to 80 of about 32,259 (328)

R-from-T as a common mechanism of arrhythmia initiation in long QT syndromes [PDF]

, 2019
Background: Long QT syndromes (LQTS) arise from many genetic and nongenetic causes with certain characteristic ECG features preceding polymorphic ventricular tachyarrhythmias (PVTs).
Liu, Michael B., Panfilov, Alexander, Qu, Zhilin, Vandersickel, Nele   +3 more
core   +2 more sources

Advancing Clinical Medicine with Raman Spectroscopy: Current Trends and Future Perspectives

Advanced Photonics Research, EarlyView.
Raman spectroscopy and microscopy may become excellent tools in clinical medicine, including hematology, oncology, infectious diseases, neurology, gastroenterology, reproductive medicine, rheumatology, and cardiovascular research. However, many challenges such as signal interference, standardization issues, and limited clinical application need to be ...
Jiří Bufka, Lenka Vaňková, Josef Sýkora, Věra Křížková, Jan Schwarz, Petr Bouř   +5 more
wiley   +1 more source

PCSK9 Loss‐of‐Function Disrupts Cellular Microfilament Network via LIN28A/HES5/JMY Axis in Neural Tube Defects

Advanced Science, EarlyView.
PCSK9 acts as a molecular chaperone promoting LIN28A lysosomal degradation. LIN28A elevates transcription factor HES5, increasing JMY expression. PCSK9 loss causes neural tube defects (NTDs) by disrupting the LIN28A/HES5/JMY axis, and high JMY disorganizes the neural progenitor cell microfilament network, leading to incomplete neural tube structure in ...
Xiaoshuai Li, Rui Wang, Wenting Luo, Hui Gu, Tianchu Huang, Qiushi Wang, Zhengwei Yuan   +6 more
wiley   +1 more source

The Relationship between Depression Symptoms and Physical Activity in Children with Idiopathic Ventricular Extrasystoles

Medicina
Background and Objectives: Depression in childhood often co-occurs with anxiety disorders and a range of somatic symptoms. Recent studies have identified physical activity as a target for preventing the onset of depression.
Rita Kunigeliene, Odeta Kinciniene, Vytautas Usonis, Sigita Lesinskiene   +3 more
doaj   +1 more source

Pseudo 2:1 AV Block From Acquired Long QT Syndrome From Eating Clay

JACC: Case Reports, 2023
Age-related degeneration of the cardiac conduction system is an important cause of heart block and a leading indication for permanent pacemaker implantations.
Kabo Mojela, MBChB, MMed, Philasande Mkoko, MBChB, MMed, MPhil, Cert Cardio, ECES   +2 more
doaj   +1 more source

Efficacy of pimobendan in the prevention of congestive heart failure or sudden death in doberman pinschers with preclinical dilated cardiomyopathy (the PROTECT study) [PDF]

, 2012
<p>Background: The benefit of pimobendan in delaying the progression of preclinical dilated cardiomyopathy (DCM) in Dobermans is not reported.</p> <p>Hypothesis: That chronic oral administration of pimobendan to Dobermans with ...
Boswood, A., Braz-Ruivo, L., Culshaw, G.J., Dukes-McEwan, J., Estrada, A., French, A.T., Gordon, S.G., Loureiro, J., O'Grady, M.R., O'Sullivan, M.L., Oyama, M.A., Patteson, M., Smith, A., Summerfield, N.T., Watson, P.J., Willis, R.   +15 more
core   +1 more source

A Redox‐Active and Electroactive Hydrogel Enabled by an Integrated PEDOT@PMOF Nanofiller for Post‐Infarct Myocardial Repair

Advanced Science, EarlyView.
An integrated nanoparticle PEDOT@PMOF is constructed as a redox‐active nanozyme and electroactive nanofiller in a cell‐affinity hydrogel platform for acute MI treatment. It is demonstrated that MOF‐based nanozymes have good catalytic ability, and the incorporation of PEDOT increases the conductivity.
Shuyi He, Linyu Long, Wenqi Liu, Zhicun Wang, Xiaofeng Wu, Li Yang, Yunbing Wang   +6 more
wiley   +1 more source

Ventricular dyssynchrony as a cause of structural disease in the heart of Dorper sheep

Onderstepoort Journal of Veterinary Research, 2004
Ventricular dyssynchrony is a disturbance of the normal, organized electromechanical coupling of the two ventricles. This condition has many causes, such as left bundle branch block, ventricular preexcitation, right ventricular pacing and right ...
J. Ker, E.C. Webb, C.F. Van der Merwe
doaj   +1 more source

Percutaneous pulmonary valve implantation alters electrophysiologic substrate [PDF]

, 2016
BACKGROUND: Percutaneous pulmonary valve implantation (PPVI) is first‐line therapy for some congenital heart disease patients with right ventricular outflow tract dysfunction.
Avari Silva, Jennifer N, Balzer, David T, Nguyen, Hoang H, Nicolas, Ramzi, Shahanavaz, Shabana, Van Hare, George F   +5 more
core   +2 more sources

PM2.5 Induce Endothelial‐Mesenchymal Transition and Cardiac Fibrosis via the NCOA4‐Mediated Ferritinophagy

Advanced Science, EarlyView.
This study primarily reveals that PM2.5‐derived Fe‐containing particles, particularly magnetite, are specifically enriched in the heart. Here, they interact with NCOA4 in endothelial cells, disrupt iron homeostasis by enhancing ferritinophagy, and subsequently trigger the process of EndMT through the NCOA4/KLF5 pathway.
Qinglin Sun, Mengyuan Wang, Lin Liu, Ruiyang Ding, Kanglin Yan, Shiqian Liu, Xiaoke Ren, Qing Xu, Zhiwei Sun, Qian Liu, Yi Yang, Junchao Duan   +11 more
wiley   +1 more source