Results 91 to 100 of about 114,348 (307)

Community health worker-led household screening and management of neonatal hyperbilirubinemia in rural Bangladesh: a cluster randomized control trial protocol [version 2; peer review: 1 approved, 2 approved with reservations]

open access: yesGates Open Research
Background Extreme hyperbilirubinemia leading to neurologic disability and death is disproportionately higher in low- and middle-income countries (LMIC) such as Bangladesh, and is largely preventable through timely treatment.
Mohammod Shahidullah   +13 more
doaj   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

open access: yesFEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli   +2 more
wiley   +1 more source

ABO blood group antigens influence host–microbe interactions and risk of early spontaneous preterm birth

open access: yesnpj Biofilms and Microbiomes
The mechanisms by which vaginal microbiota shape spontaneous preterm birth (sPTB) risk remain poorly defined. Using electronic clinical records data from 74,913 maternities in conjunction with metaxanomic (n = 596) and immune profiling (n = 314) data, we
Katherine E. Mountain   +30 more
doaj   +1 more source

Epidemiology and aetiology of maternal bacterial and viral infections in low- and middle-income countries [PDF]

open access: yesJournal of Global Health, 2011
Maternal morbidity and mortality in low and middle income countries has remained exceedingly high. However, information on bacterial and viral maternal infections, which are important contributors to poor pregnancy outcomes, is sparse and poorly ...
Prasad Palani Velu   +8 more
doaj  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

The cost of prematurity [PDF]

open access: yes, 2014
Prematurity is still a major problem not only in the field of obstetrics and perinatal medicine but also for the society as a whole, not to mention the burdens for the concerned infants and their families.(1) The financial burden of preterm birth (PB)
Trajkova, Kornelija   +4 more
core   +2 more sources

Retinopathy of Prematurity: A Brief Review of Literature

open access: yes, 2017
Retinopathy of prematurity is a vaso-proliferative retinal disorder occurring in preterm infants. With the increase in the survival of preterm infants, retinopathy of prematurity has become a major cause of childhood blindness worldwide.
Nassiri, Nader, Hashemieh, Mozhgan
core   +1 more source

Ethical Foreground and Background in Adult Educator Work

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Adult educators work in a complex ethical environment. The very act of contributing to the learning of another is fraught with moral overtones. In this paper we consider the ethical dimensions of adult educator practice by distinguishing the ethical features of the context or ‘background’ of practice from the ethical capabilities and decision ...
Steven Hodge, Sonal Nakar
wiley   +1 more source

Metabolic Bone Disease of Prematurity: Diagnosis and Management

open access: yesFrontiers in Pediatrics, 2019
Metabolic Bone Disease (MBD) of prematurity is a multifactorial disorder commonly observed in very low birth weight (VLBW, <1,500 g) newborns, with a greater incidence in those extremely low birth weight (ELBW, <1,000 g).
Maria Felicia Faienza   +6 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

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