Results 81 to 90 of about 110,311 (309)

SmartPlus: a computer-based image analysis method to predict continuous-valued vascular abnormality index in Retinopathy of Prematurity

International Journal of Retina and Vitreous
Plus disease is characterized by abnormal changes in retinal vasculature of premature infants. Presence of Plus disease is an important criterion for identifying treatment-requiring cases in Retinopathy of Prematurity (ROP).
Sayed Mehran Sharafi, Nazanin Ebrahimiadib, Ramak Roohipourmoallai, Afsar Dastjani Farahani, Marjan Imani Fooladi, Golnaz Gharehbaghi, Elias Khalili Pour   +6 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Pharmacological Approach for Treatment of Retinopathy of Prematurity

, 2012
Current standard of screening examination for retinopathy of prematurity (ROP) is determined in international guidelines. The criteria for classification and therapy are also determined in international guidelines, and currently, retinal laser ...
İmren Akkoyun
core   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Early applicability of retinopathy of prematurity score (ROPScore) and serum insulin growth factor-1 (IGF-1) for predicting treatment-requiring retinopathy of prematurity: a prospective cohort study

Egyptian Pediatric Association Gazette
Background Retinopathy of prematurity is a leading cause of blindness especially in developing countries where the accessibility to screening may not be available.
Aliaa Adel Ali, Nancy Abd El-Salam Ahmed Gomaa, Basma Samir Kamil, Ahmed Awadein, Heba Baz, Esraa Ahmed Elmazzahy   +5 more
doaj   +1 more source

Factors associated with delayed vascular maturation in infants with retinopathy of prematurity not requiring treatment

Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2016
Purpose: The aim of this study is to determine risk factors associated with delayed regression of retinopathy of prematurity and prolonged vascular completion in patients not requiring treatment.
Ebru Esen, Selcuk Sizmaz, Hacer Yapicioglu, Ferda Ozlu, Kemal Yar, Ilker Unal, Nihal Demircan   +6 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Community health worker-led household screening and management of neonatal hyperbilirubinemia in rural Bangladesh: a cluster randomized control trial protocol [version 2; peer review: 1 approved, 2 approved with reservations]

Gates Open Research
Background Extreme hyperbilirubinemia leading to neurologic disability and death is disproportionately higher in low- and middle-income countries (LMIC) such as Bangladesh, and is largely preventable through timely treatment.
Mohammod Shahidullah, Md. Mahbubul Hoque, Muhammad Shariful Islam, Vinod K Bhutani, Eric M. Foote, Gary L Darmstadt, Mahbubur Rahman, Farjana Jahan, Tasnim Ahmed, Sarker Masood Parvez, Farzana Yeasmin, Rezaul Hasan, Sk Masum Billah, Shams El Arifeen   +13 more
doaj   +1 more source

Epidemiology and aetiology of maternal bacterial and viral infections in low- and middle-income countries [PDF]

Journal of Global Health, 2011
Maternal morbidity and mortality in low and middle income countries has remained exceedingly high. However, information on bacterial and viral maternal infections, which are important contributors to poor pregnancy outcomes, is sparse and poorly ...
Prasad Palani Velu , Courtney A. Gravett , Tom K. Roberts , Thor A. Wagner , Jian Shayne F. Zhang , Craig E. Rubens , Michael G. Gravett , Harry Campbell , Igor Rudan   +8 more
doaj  

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source