Results 41 to 50 of about 1,199 (179)

Discovering Uncharted Binding Pockets on E3 Ligases Leads to the Identification of FBW7 Allosteric Modulators

open access: yesAdvanced Science, Volume 12, Issue 39, October 20, 2025.
A computational approach to identify and characterize ligandable binding pockets on E3 ligases is presented. As a validation case, the first low‐micromolar small moleculesthat bind to the FBW7 E3 ligase are identified and confirmed to bind at the intended site.
Míriam Martínez‐Cartró   +13 more
wiley   +1 more source

Premios y castigos en la educación. ¿Barreras o estrategias para aprender?

open access: yesRevista Iberoamericana de Educación, 2010
Los premios y los castigos son comunes en la vida cotidiana. En el campo de la educación son los estudiantes quienes, con frecuencia, viven este tipo de procedimientos; también los docentes se encuentran sujetos a la aplicación de lo que algunos ...
Arturo Perrusquía Reséndiz
doaj  

Comparative Analysis of Shear Bond Strength of Four Adhesive Systems on Primary Dentin

open access: yesClinical and Experimental Dental Research, Volume 11, Issue 5, October 2025.
ABSTRACT Objective This study aimed to conduct a comparative evaluation of the shear bond strength of etch and rinse (Single Bond 2), two‐step self‐etch (Clearfil SE) and one‐step self‐etch (Go Bond SDI and G‐Premio Bond) bonding agents applied to primary teeth, using a universal testing machine.
Faezeh Abedi   +3 more
wiley   +1 more source

Los Premios

open access: yes, 2021
Número de la publicación ...
Gladys S., Onega, Onega, Gladys S.
openaire   +1 more source

Immunoproteasome Inhibition Positively Impacts the Gut‐Muscle Axis in Duchenne Muscular Dystrophy

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 5, October 2025.
ABSTRACT Background Duchenne Muscular Dystrophy (DMD) features immune‐muscle crosstalk, where muscle fibre degeneration enhances pro‐inflammatory macrophage infiltration, worsening inflammation and impairing regeneration. Methods We investigated the impact of immunoproteasome (IP) inhibition on the gut‐muscle axis in mdx mice, a well‐established model ...
Andrea Farini   +17 more
wiley   +1 more source

Os prêmios qualidade

open access: yesRevista Principia, 2013
O presente estudo visa apresentar as principais características dos prêmios de qualidade que deram origem ao Prêmio Nacional de Qualidade, atribuído anualmente no Brasil às empresas que mais se destacaram dentro de padrões de implantação da qualidade.
Marília De Franceschi Neto Domingos
doaj   +1 more source

Insights into the clinical, platelet and genetic landscape of inherited thrombocytopenia with malignancy risk

open access: yesBritish Journal of Haematology, Volume 207, Issue 4, Page 1565-1577, October 2025.
Inherited thrombocytopenia (IT) caused by germline variants in RUNX1, ETV6 or ANKRD26 carries a high risk of developing haematological malignancy. This study examined the clinical, platelet and molecular characteristics of 66 patients with these conditions, who carried 24 distinct genetic variants in the corresponding genes.
Ana Marín‐Quílez   +34 more
wiley   +1 more source

Prueba Premios 2

open access: yesTecnología, Ciencia y Educación, 2022
...
Alicia Carmen López Mendoza
doaj  

Enhancement of Composite Resin Bonding on Dental Tissues Using Cold Atmospheric Plasma Discharge: A Systematic Literature Review and Proposal for a Redaction Grid

open access: yesPlasma Processes and Polymers, Volume 22, Issue 9, September 2025.
The application of cold atmospheric plasma in dentistry for teeth restauration appears to be a beneficial approach for improving the bond strength of composite resins. This systematic review also introduces the PLASDENT grid, a reporting tool to standardize experimental protocols and facilitate future comparisons in dental plasma research. ABSTRACT The
Thibault Canceill   +6 more
wiley   +1 more source

El cuerpo del monstruo en "Los Premios" de Julio Cortázar. [PDF]

open access: yesOgigia, 2008
ENGLISH: In this paper, we intend to analyze the first novel of Julio Cortázar, Los Premios, published in 1960. Our analysis is centered on the figure of the monster that is concealed in the description and in the actions of the characters.
María Luiza Teixeira Batista
doaj  

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