Results 41 to 50 of about 1,199 (179)
A computational approach to identify and characterize ligandable binding pockets on E3 ligases is presented. As a validation case, the first low‐micromolar small moleculesthat bind to the FBW7 E3 ligase are identified and confirmed to bind at the intended site.
Míriam Martínez‐Cartró +13 more
wiley +1 more source
Premios y castigos en la educación. ¿Barreras o estrategias para aprender?
Los premios y los castigos son comunes en la vida cotidiana. En el campo de la educación son los estudiantes quienes, con frecuencia, viven este tipo de procedimientos; también los docentes se encuentran sujetos a la aplicación de lo que algunos ...
Arturo Perrusquía Reséndiz
doaj
Comparative Analysis of Shear Bond Strength of Four Adhesive Systems on Primary Dentin
ABSTRACT Objective This study aimed to conduct a comparative evaluation of the shear bond strength of etch and rinse (Single Bond 2), two‐step self‐etch (Clearfil SE) and one‐step self‐etch (Go Bond SDI and G‐Premio Bond) bonding agents applied to primary teeth, using a universal testing machine.
Faezeh Abedi +3 more
wiley +1 more source
Immunoproteasome Inhibition Positively Impacts the Gut‐Muscle Axis in Duchenne Muscular Dystrophy
ABSTRACT Background Duchenne Muscular Dystrophy (DMD) features immune‐muscle crosstalk, where muscle fibre degeneration enhances pro‐inflammatory macrophage infiltration, worsening inflammation and impairing regeneration. Methods We investigated the impact of immunoproteasome (IP) inhibition on the gut‐muscle axis in mdx mice, a well‐established model ...
Andrea Farini +17 more
wiley +1 more source
O presente estudo visa apresentar as principais características dos prêmios de qualidade que deram origem ao Prêmio Nacional de Qualidade, atribuído anualmente no Brasil às empresas que mais se destacaram dentro de padrões de implantação da qualidade.
Marília De Franceschi Neto Domingos
doaj +1 more source
Inherited thrombocytopenia (IT) caused by germline variants in RUNX1, ETV6 or ANKRD26 carries a high risk of developing haematological malignancy. This study examined the clinical, platelet and molecular characteristics of 66 patients with these conditions, who carried 24 distinct genetic variants in the corresponding genes.
Ana Marín‐Quílez +34 more
wiley +1 more source
The application of cold atmospheric plasma in dentistry for teeth restauration appears to be a beneficial approach for improving the bond strength of composite resins. This systematic review also introduces the PLASDENT grid, a reporting tool to standardize experimental protocols and facilitate future comparisons in dental plasma research. ABSTRACT The
Thibault Canceill +6 more
wiley +1 more source
El cuerpo del monstruo en "Los Premios" de Julio Cortázar. [PDF]
ENGLISH: In this paper, we intend to analyze the first novel of Julio Cortázar, Los Premios, published in 1960. Our analysis is centered on the figure of the monster that is concealed in the description and in the actions of the characters.
María Luiza Teixeira Batista
doaj

