Results 221 to 230 of about 115,105 (293)

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Daily Protein Restriction Under Different Protein Levels in Whiteleg Shrimp (<i>Penaeus vannamei</i>): Growth, Digestive System, Gene Expression, and Health. [PDF]

Aquac Nutr
Sotoudeh E, Khalili L, Zoab M, Bahmani Z, Esmaeili N.   +4 more
europepmc   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Alteration of Acid-Binding Capacity of Various Nursery Pig Diets and Its Influence on Properties of Digesta Along the Gastrointestinal Tract. [PDF]

J Anim Physiol Anim Nutr (Berl)
Choi H, Kim SW.
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Effects of L-Carnitine and Fenofibrate on Lipid Metabolism, Oxidative Status, and Flesh Quality of Yellow River Carp (<i>Cyprinus carpio</i>). [PDF]

Aquac Nutr
Zhao M, Zhi S, Qin C, Yang L, Nie G.
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Optimizing 3D-printed core-shell hydrogel system for probiotic protection: stability under in vitro digestion conditions and during storage. [PDF]

J Biol Eng
Truong-Le QA, Lee SO, Ubeyitogullari A.
europepmc   +1 more source

Optimizing Peafowl (Pavo cristatus) Fertility and Chick Growth With Mealworm-Based Feed Supplementation. [PDF]

Vet Med Sci
Khan SZ, Al-Khalaifah H, Khan H, Ullah Khan R, Naz S, Abudabos A, A Alhidary I.   +6 more
europepmc   +1 more source

Enhanced efficacy of tylvalosin tartrate enteric-coated granules against <i>Mycoplasma hyopneumoniae</i> in pigs: <i>in vitro</i> activity and clinical dosage optimization. [PDF]

Front Microbiol
Li J, Zhou X, Wang W, Zhang H, Bai Y, Zhai B, Cheng F, Hu R, Li B, Zhou Y, Cao M, Ma T, Zhu Z, Zhang J.   +13 more
europepmc   +1 more source