Results 81 to 90 of about 4,172 (194)

A Model of Combined Exposure to Nicotine and Tetrahydrocannabinol via Electronic Cigarettes in Pregnant Rats

open access: yesFrontiers in Neuroscience, 2022
Nicotine and cannabis are two of the most commonly consumed licit and illicit drugs during pregnancy, often consumed together via e-cigarettes. Vaping is assumed to be a safer alternative than traditional routes of consumption, yet the potential ...
Kristen R. Breit   +7 more
doaj   +1 more source

Transfer of paracetamol across the placenta and fetal blood–brain barriers and its safety for use in pregnancy

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Paracetamol (acetaminophen) is commonly taken during pregnancy for pain and fever. To gain a more comprehensive understanding of paracetamol's effects during pregnancy, several elements need to be examined including the transfer of paracetamol across the placenta and into the developing brain, the short‐ and long‐term effects of ...
Yifan Huang, Liam Koehn
wiley   +1 more source

Risk of adverse neonatal outcomes after combined prenatal cannabis and nicotine exposure. [PDF]

open access: yes
Importance: The prevalence of cannabis use in pregnancy is rising and is associated with adverse perinatal outcomes. In parallel, combined prenatal use of cannabis and nicotine is also increasing, but little is known about the combined impact of both ...
Shorey-Kendrick, Lyndsey E   +10 more
core   +1 more source

The Effects of Prenatal Cannabis Exposure on the Basolateral Amygdala [PDF]

open access: yes, 2022
Clinical and preclinical studies indicate prenatal cannabis exposure (PCE) pathologically affects fetal brain development and may increase vulnerability to neuropsychiatric disorders, including schizophrenia and mood/anxiety disorders. In review research from our lab suggests that fetal exposure to Δ9-THC sex-selectively impairs mesocorticolimbic (MCL)
openaire  

Severe Holoprosencephaly With Arhinencephaly in A Liveborn Neonate: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 7, July 2026.
Physical examination revealed a‐hypotelorism, b‐arhinia, and c‐cleft lip and palate. ABSTRACT Holoprosencephaly (HPE) is a rare congenital brain malformation resulting from incomplete separation of the cerebral hemispheres. It has an estimated prevalence of 1 in 10,000 live births.
Sarah K. Kebbeh, Hamdi I. Nawfal
wiley   +1 more source

Asthma in Children With Congenital Lung Malformations: A Population‐Based Case‐Control Study

open access: yesPediatric Pulmonology, Volume 61, Issue 7, July 2026.
ABSTRACT Background Congenital lung malformations (CLM) are developmental anomalies that may predispose to respiratory morbidity. Their association with asthma remains unclear, largely due to small series and the lack of population‐based controls. Objective To evaluate asthma prevalence and related outcomes in children with CLM compared to population ...
Louis W. J. Dossche   +6 more
wiley   +1 more source

Nicotine Exposure During Pregnancy and Postnatal Cognitive Outcomes: A Systematic Review and Meta‐Analysis

open access: yesActa Paediatrica, Volume 115, Issue 7, Page 1413-1428, July 2026.
ABSTRACT Aim Nicotine exposure during pregnancy interferes with critical periods of foetal brain development, disrupting the timing and functioning of neurodevelopment. This systematic review and meta‐analysis aims to evaluate the effect of prenatal nicotine exposure on postnatal cognitive outcomes.
Deimantė Baguckaitė   +2 more
wiley   +1 more source

EFFECTS OF CANNABIS CONSTITUENTS ON OVARIAN HEALTH AND FUNCTION: A FOCUS ON PRENATAL EXPOSURE [PDF]

open access: yes, 2022
This thesis is prepared in the “sandwich” format as outlined in the “Guide for the preparation of Master’s and Doctoral Theses” available through the School of Graduate Studies at McMaster University.
Martínez, Annia
core  

Dissecting the polygenic architecture of psychopathology via singular value decomposition of eight psychiatric genome‐wide association studies and evaluation of component‐based polygenic scores

open access: yesGeneral Psychiatry, Volume 39, Issue 3, June 2026.
ABSTRACT Background Current research suggests that genetic risk for psychiatric disorders is largely due to distinct combinations of many common variants shared by different disorders. This points to the existence of latent components affecting different dimensions of psychopathology.
Fernando Facal   +2 more
wiley   +1 more source

Quantification and prediction of human fetal (-)-Δ9-tetrahydrocannabinol/(±)-11-OH-Δ9-tetrahydrocannabinol exposure during pregnancy to inform fetal cannabis toxicity

open access: yesNature Communications
Prenatal cannabis use is associated with neurodevelopmental deficits, likely due to exposure to the psychoactive cannabinoid, (-)-Δ9-tetrahydrocannabinol, and its active metabolite, (±)-11-OH-Δ9-tetrahydrocannabinol.
Aditya R. Kumar   +6 more
doaj   +1 more source

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