Results 171 to 180 of about 134,201 (266)

Integrated one‐pot CRISPR‐Cas detection: Addressing strategies and future prospects

Interdisciplinary Medicine, EarlyView.
Integrated one‐pot CRISPR‐Cas detection significantly simplifies workflows, reduces cross‐contamination risks, and shortens turnaround times, making it highly suitable for point‐of‐care testing (POCT) and resource‐limited settings. Key challenges include system compatibility issues between Cas proteins and isothermal amplification, limited multiplexing
Jian Zhou, Xuemei Ren, Yingjie Ren, Ruiping Wu, Ruiman Geng, Le Chen, Zhuo Li   +6 more
wiley   +1 more source

‘Pre‐Technologies’ and the Lifeworld: Assistive Technologies as ‘Pre‐Technologies’ for Self‐Formation as Freedom

Journal of Applied Philosophy, EarlyView.
ABSTRACT This article identifies assistive technologies (ATs) as ‘pre‐technologies’ mediating access to other technologies for disabled subjects (DSs). The motivation is to show that without ATs, DSs cannot be said to have the same level of access to freedom and self‐forming activities as able‐bodied subjects.
Sarel Marais
wiley   +1 more source

Lactation, Childrearing, and Gender Justice

Journal of Applied Philosophy, EarlyView.
ABSTRACT In this article, I discuss the significance of early infant feeding choices for the goal of gender justice. Focusing on human lactation practices, I identify Exclusive Gestational Nursing (EGN) as the norm in advanced industrial societies, which creates the expectation and permission for gestators, and only gestators, to nurse children, and ...
Jenny Brown
wiley   +1 more source

Paternal Exposure to the Neonicotinoid Pesticide Clothianidin Alters Sperm MicroRNA Profiles in Mice and Intergenerationally Reduces Locomotor Activity in Male Offspring

Journal of Applied Toxicology, EarlyView.
ABSTRACT Accumulating evidence suggests that paternal environmental factors have epigenetic effects on sperm and influence offspring. Neonicotinoid pesticides (NNs), which are widely used around the world, are known to affect offspring phenotypes through maternal exposure in mice, but the effect of the paternal exposure remains unknown.
Makiko Ito, Tetsushi Hirano, Sarika Nunobiki, Ayano Yoshimoto, Yukako Hara, Yuya Ishida, Sakura Yonoichi, Youhei Mantani, Toshifumi Yokoyama, Yoshiaki Tabuchi, Yoshinori Ikenaka, Nobuhiko Hoshi   +11 more
wiley   +1 more source

Prenatal Exposure to Air Pollution and Risk for Attention-Deficit/hyperactivity Disorder in Children. [PDF]

Res Child Adolesc Psychopathol
Kaur S, Canals-Sans J, Morales-Hidalgo P, Guxens M, Petricola S, Arija V.   +5 more
europepmc   +1 more source

Health Biomarkers of Pesticide Exposure in Rural Populations of Santa Fe, Argentina: Oxidative Stress and Genotoxicity

Journal of Applied Toxicology, EarlyView.
ABSTRACT The present study aimed to quantify pesticide residues in environmental matrices and plasma and to evaluate their potential effects on oxidative stress and DNA damage in rural populations of Santa Fe province. Soil and rainwater samples were collected, and biological samples and semistructured surveys were obtained from volunteers in three ...
María Priscila Dechiara, Carlina Leila Colussi, Lucía Magdalena Odetti, Damián Marino, María Fernanda Simoniello   +4 more
wiley   +1 more source

Placental MRI texture features in prenatal exposure to opioids and tobacco. [PDF]

Sci Rep
Class JA, Vishnubhotla RV, Haas DM, Hull IW, Sadhasivam S, Radhakrishnan R.   +5 more
europepmc   +1 more source

Toxic Effects of Bisphenol A and Its Analogs on Ovarian Structure and Function: A Narrative Review of Ovary‐Focused Studies

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) is a widely used industrial chemical found in polycarbonate plastics and epoxy resins and is recognized for its endocrine‐disrupting properties. Human exposure is common due to its presence in food packaging and everyday products. As BPA use has been restricted, structurally similar compounds such as BPS, BPB, BPAF, and BADGE
Nurbanu Zengin, Marwa Tawfıq Ahmed Alsalım, Muhammed Canik, Sevda Bağdatlı, Nazan Deniz Yön   +4 more
wiley   +1 more source

Associations of prenatal exposure to maternal autoimmune disorders with a wide spectrum of psychiatric and neurodevelopmental disorders in offspring-a nationwide cohort study. [PDF]

Hum Reprod Open
Skott E, Cai W, Stiernborg M, Fogdell-Hahn A, Giacobini M, Gissler M, Nivins S, Lavebratt C.   +7 more
europepmc   +1 more source

Investigation of Specific IgG‐Secreting Cells in Congenital Toxoplasmosis: The TOXODIAG Study

Journal of Clinical Laboratory Analysis, EarlyView.
This study addressed the difficulty of establishing a postnatal biological diagnosis of congenital toxoplasmosis, particularly in the absence of toxoplasmosis monitoring during pregnancy, as is the case in many countries. Our work presents an ELISPOT (Enzyme‐Linked Immunospot) method adapted for the detection of B lymphocytes primed to produce IgG ...
F. Migot‐Nabias, N. Beldjoudi, K. Bailly, M. Andrieu, M. Surenaud, K. Gbedande, C. Couffignal, L. Mandelbrot, H. Yera, S. Houzé, M. Dambrun, TOXODIAG Study Group, E. Akrich, O. Anselem, S. Bani, A. Benbara, J. Colombe, A.‐M. Darras, L. Dubois, N. Ettalhaoui, H. Jabbarian, J.‐M. Jouannic, S. Le Levier, S. Letrou, P. Maurice, A. Oubahim, D. Oultache, J. Sibiude, M. Valentin   +28 more
wiley   +1 more source