Results 211 to 220 of about 1,912,395 (308)

Cerebral organoids as a platform to model prenatal exposure to drugs of abuse. [PDF]

Neural Regen Res
Keegan L, Montwill K, Kennedy C, McMahon CL, Davis JL, Murphy KJ.   +5 more
europepmc   +1 more source

Toxic Effects of Bisphenol A and Its Analogs on Ovarian Structure and Function: A Narrative Review of Ovary‐Focused Studies

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) is a widely used industrial chemical found in polycarbonate plastics and epoxy resins and is recognized for its endocrine‐disrupting properties. Human exposure is common due to its presence in food packaging and everyday products. As BPA use has been restricted, structurally similar compounds such as BPS, BPB, BPAF, and BADGE
Nurbanu Zengin, Marwa Tawfıq Ahmed Alsalım, Muhammed Canik, Sevda Bağdatlı, Nazan Deniz Yön   +4 more
wiley   +1 more source

From Prenatal Exposure to Adult Sexual Dysfunction: The Impact of Plastic-Derived Endocrine Disruptors on Testosterone Homeostasis and Erectile Function. [PDF]

Toxics
Stavros S, Christopoulos P, Kokkosi E, Moustakli E, Zikopoulos A, Potiris A, Daskalaki MA, Arkoulis I, Anagnostaki I, Vassilaki I, Kathopoulis N, Daskalakis G, Drakakis P.   +12 more
europepmc   +1 more source

Assessing Metabolic and Reproductive Consequences of Prenatal Paracetamol Exposure in Female CD1 Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Paracetamol is a widely used analgesic during pregnancy; however, emerging evidence suggests it may act as an endocrine/metabolism disrupting compound. Using an F1 female CD1 mouse model, this study scrutinized the long‐term metabolic and reproductive consequences linked to intrauterine paracetamol exposure.
Bita Entezari, Deniz Bozdag, Elif İnce‐Erguc, Aylin Buhur, Cansin Sirin Tomruk, Suna Sabuncuoglu, Altug Yavasoglu, Hande Gurer‐Orhan   +7 more
wiley   +1 more source

Bisphenol M Induces Dose‐Dependent Hepatic Injury and Fibrotic Remodeling in Female Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT The safety of bisphenol analogs as alternatives to bisphenol A (BPA) is increasingly concerning. This study investigated the hepatotoxic effects of bisphenol M (BPM), a widely used BPA substitute, in 6‐week‐old female BALB/c mice exposed to 2.5, 5, and 10 mg/kg/day intraperitoneally for 14 days. Hepatic changes were assessed via histopathology,
Muhammed Canik, Asuman Deveci Ozkan, Tuğba Kotil, Nazan Deniz Yön   +3 more
wiley   +1 more source

Prenatal Exposure to Acid-Suppressive Medications and Incident Risk of Inflammatory Bowel Disease in Children.

JAMA Netw Open
Oh J, Park J, Kim H, Jo H, Lee K, Jo Y, Hong S, Lee S, Woo S, Hwang Y, Lee J, Kim TH, Lee H.   +12 more
europepmc   +1 more source

Effects of Glyphosate and Glyphosate‐Based Herbicides on the Mammalian Gut Microbiome: A Critical Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Glyphosate has long been considered to pose negligible direct risk to mammals on the grounds that its molecular target, 5‐enolpyruvylshikimate‐3‐phosphate synthase (EPSPS), of the shikimate pathway, is absent from animal cells. This rationale is inaccurate as a complete toxicological argument, because the shikimate pathway is present in some ...
Robin Mesnage
wiley   +1 more source

Prenatal exposure to asthma medications and risk of neurodevelopmental disorders and educational difficulties: A systematic review and meta-analysis. [PDF]

PLoS Med
Shakhshir LA, Karain A, Pell JP, Hastie CE, Nelson SM, Fleming M.   +5 more
europepmc   +1 more source

Response: MicroRNA‐210 level as a biomarker for pre‐eclampsia severity: A systematic review and meta‐analysis

International Journal of Gynecology &Obstetrics, EarlyView.
Dávid Márai, Isabel Pinto Amorim das Virgens, Ádám Vincze, Mahmoud Obeidat, Péter Hegyi, Mikolt Bakony, Zsófia Réka Erdélyi, Zsolt Melczer, Sándor Valent   +8 more
wiley   +1 more source

First‐Trimester CBC‐Derived Inflammatory Indices for Prediction of Miscarriage: A Retrospective Cohort Study

Journal of Clinical Laboratory Analysis, EarlyView.
Maternal age was an independent predictor of miscarriage, and first‐trimester NLR and SII provided significant incremental predictive value. Because these indices are routinely derived from standard CBC testing without additional cost, they may serve as practical adjuncts to clinical risk factors for early miscarriage risk stratification.
Suchada Wattanaploy, Suchaya Luewan, Theera Tongsong   +2 more
wiley   +1 more source