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Developmental origins of non-communicable disease: Implications for research and public health
This White Paper highlights the developmental period as a plastic phase, which allows the organism to adapt to changes in the environment to maintain or improve reproductive capability in part through sustained health.
Barouki Robert +4 more
doaj +1 more source
Alteration of rat fetal cerebral cortex development after prenatal exposure to polychlorinated biphenyls. [PDF]
Polychlorinated biphenyls (PCBs) are environmental contaminants that persist in environment and human tissues. Perinatal exposure to these endocrine disruptors causes cognitive deficits and learning disabilities in children.
Elise Naveau +8 more
doaj +1 more source
Developmental and functional effects of steroid hormones on the neuroendocrine axis and spinal cord [PDF]
This review highlights the principal effects of steroid hormones at central and peripheral levels in the neuroendocrine axis. The data discussed highlight the principal role of oestrogens and testosterone in hormonal programming in relation to sexual ...
Gonzalez Deniselle, Maria Claudia +4 more
core +2 more sources
Disrupted Social Hierarchy in Prenatally Valproate-Exposed Autistic-Like Rats
Autism spectrum disorder (ASD) is characterized by impaired socio-communicational function, repetitive and restricted behaviors. Valproic acid (VPA) was reported to increase the prevalence of ASD in humans as a consequence of its use during pregnancy ...
Péter Pelsőczi +8 more
doaj +1 more source
Studies assessing associations between prenatal exposure to antidepressants, maternal depression, and offspring DNA methylation (DNAm) have been inconsistent.
Emilie Willoch Olstad +4 more
doaj +1 more source
Metabotropic glutamate 2/3 receptors and epigenetic modifications in psychotic disorders: a review [PDF]
Schizophrenia and Bipolar Disorder are chronic psychiatric disorders, both considered as "major psychosis"; they are thought to share some pathogenetic factors involving a dysfunctional gene x environment interaction.
Grayson, Danis R +4 more
core +2 more sources
Cardiovascular disease in a cohort exposed to the 1940-45 Channel Islands occupation [PDF]
BACKGROUND To clarify the nature of the relationship between food deprivation/undernutrition during pre- and postnatal development and cardiovascular disease (CVD) in later life, this study examined the relationship between birth weight (as a marker ...
A Forsdahl +43 more
core +4 more sources
Background We systematically reviewed and chronicled exposures and outcomes measured in the maternal and birth cohort studies in the Gulf Cooperation Council (GCC) countries and quantitatively summarized the weighted effect estimates between maternal ...
Rami H. Al-Rifai +6 more
doaj +1 more source
INTRODUCTION: Prenatal tobacco exposure interferes with neonatal outcomes. OBJECTIVE: To determine the neonatal neurobehavioral effects of in utero tobacco exposure.
Marina C. M. Barros +4 more
doaj +1 more source
Children's exposure to mercurial skin lightening agents at any time during their development, from intra-uterine to early developmental life, can lead to severe detrimental health effects.
Rebecca Murerwa +3 more
doaj +1 more source

