Results 21 to 30 of about 10,921,254 (269)

Maternal and birth cohort studies in the Gulf Cooperation Council countries: a systematic review and meta-analysis

open access: yesSystematic Reviews, 2020
Background We systematically reviewed and chronicled exposures and outcomes measured in the maternal and birth cohort studies in the Gulf Cooperation Council (GCC) countries and quantitatively summarized the weighted effect estimates between maternal ...
Rami H. Al-Rifai   +6 more
doaj   +1 more source

Effects of prenatal exposure to (es)citalopram and maternal depression during pregnancy on DNA methylation and child neurodevelopment

open access: yesTranslational Psychiatry, 2023
Studies assessing associations between prenatal exposure to antidepressants, maternal depression, and offspring DNA methylation (DNAm) have been inconsistent.
Emilie Willoch Olstad   +4 more
doaj   +1 more source

Impact of prenatal chlorpyrifos exposure on neurodevelopment in the first 3 years of life among inner-city children. [PDF]

open access: yes, 2006
Objective: The purpose of this study was to investigate the impact of prenatal exposure to chlorpyrifos on 3-year neurodevelopment and behavior in a sample of inner-city minority children.
Garfinkel, Robin   +8 more
core   +1 more source

Long Noncoding RNA PCALRx Interacts with Pyruvate Carboxylase to Drive Multi‐Organ Developmental Toxicity in Zebrafish Embryos Exposed to Amoxicillin

open access: yesAdvanced Science, EarlyView.
Embryonic amoxicillin exposure disrupts multi‐organ development in zebrafish larvae through a lncRNA–metabolic enzyme regulatory axis. PCALRx associates with pyruvate carboxylase, promotes PC protein ubiquitination, and impairs mitochondrial energy metabolism, while vitamin B1 partially restores PC‐centered metabolic function and developmental outcomes.
Yixue Yao   +5 more
wiley   +1 more source

Autonomic and Renal Alterations in the Offspring of Sleep-Restricted Mothers During Late Pregnancy

open access: yesClinics
OBJECTIVES: Considering that changes in the maternal environment may result in changes in progeny, the aim of this study was to investigate the influence of sleep restriction during the last week of pregnancy on renal function and autonomic responses in ...
Joyce R.S. Raimundo   +5 more
doaj   +1 more source

Timing of pubertal development in boys born with cryptorchidism and hypospadias: a nationwide cohort study

open access: yesAsian Journal of Andrology, 2019
Pubertal development may be altered in boys with cryptorchidism and hypospadias, but existing knowledge is inconsistent. Therefore, we investigated the association between cryptorchidism and hypospadias and pubertal development in a large cohort study ...
Linn Håkonsen Arendt   +5 more
doaj   +1 more source

Repurposing a Small Molecule Plant Hormone as a Tunable ON‐Switch for CAR‐T Cell Immunotherapy

open access: yesAdvanced Science, EarlyView.
By engineering a receptor system integrating the plant auxin receptor AFB1 with its co‐receptor IAA7, we enable ligand‐dependent interactions triggered by the plant hormone auxins. This design allows rapid, reversible, and dose‐dependent T cell activation, resulting in potent cytotoxicity against B‐cell lymphoma in vitro and in vivo.
Hongxiang Zeng   +16 more
wiley   +1 more source

Association between tobacco and/or alcohol consumption during pregnancy and infant development: BRISA Cohort [PDF]

open access: yesBrazilian Journal of Medical and Biological Research
Fetuses exposed to alcohol and/or tobacco are at risk for perinatal adversities. However, little is currently known about the association of the separate or concomitant use of alcohol and tobacco with infant motor and cognitive development.
M.E.A. Negrão   +7 more
doaj   +2 more sources

TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains

open access: yesAdvanced Science, EarlyView.
Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang   +14 more
wiley   +1 more source

Prenatal exposure to buprenorphine or methadone: effects on physical growth, neurological development and temperament in early childhood. [PDF]

open access: yes, 2012
Pharmaceutical maintenance with methadone is the current gold standard for pregnant women with opioid-dependence. While there are many benefits of methadone, its use during pregnancy is associated with high rates of neonatal abstinence syndrome, and long
Whitham, Justine N.
core  

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