Results 81 to 90 of about 71,374 (268)

Potential Mechanism Connecting Preeclampsia to Autism Spectrum Disorder in Offspring: The Role of Microglial Abnormalities

open access: yesFrontiers in Bioscience-Landmark
Preeclampsia (PE) is a serious complication of pregnancy characterized by chronic inflammation and immune dysregulation, which significantly increases the risk of neurodevelopmental disorders in offspring, including the autism spectrum disorder (ASD ...
Ying Zhu   +4 more
doaj   +1 more source

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

open access: yesEpilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira   +5 more
wiley   +1 more source

The multiple hit model of infantile and epileptic spasms: The 2025 update

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou   +6 more
wiley   +1 more source

Ketogenic diet for infantile epileptic spasms

open access: yesEpilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury   +3 more
wiley   +1 more source

Nicotine ameliorates schizophrenia-like cognitive deficits induced by maternal LPS exposure: a study in rats

open access: yesDisease Models & Mechanisms, 2016
Maternal exposure to infectious agents is a predisposing factor for schizophrenia with associated cognitive deficits in offspring. A high incidence of smoking in these individuals in adulthood might be, at least in part, due to the cognitive-enhancing ...
Uta Waterhouse   +3 more
doaj   +1 more source

Attitudes toward sodium valproate use, withdrawal, and counseling in people of reproductive potential: A scoping review

open access: yesEpilepsia Open, EarlyView.
Abstract Regulatory restrictions and evolving clinical guidelines have aimed to reduce sodium valproate use in people of reproductive potential over the past decade due to its teratogenic risk. While clinical evidence and policy responses are well established, stakeholder perspectives remain less explored.
Katherine Wang   +3 more
wiley   +1 more source

Neonatal outcomes and follow-up of children born to women with pregnancy-associated cancer: a prospective observational study

open access: yesBMC Pregnancy and Childbirth
Background During the last decade, there has been a growing number of cases of children born from pregnancy-associated cancer (PAC), however there are currently insufficient data on the follow up to be observed in this category of newborns.
Michele Antonio Capozza   +8 more
doaj   +1 more source

Fetal Alcohol Spectrum Disorders: an overview from the glia perspective

open access: yesFrontiers in Integrative Neuroscience, 2016
Alcohol consumption during pregnancy can produce a variety of central nervous system abnormalities in the offspring resulting in a broad spectrum of cognitive and behavioral impairments that constitute the most severe and long-lasting effects observed in
Clare J. Wilhelm   +3 more
doaj   +1 more source

Prenatal glucocorticoid exposure in rats: programming effects on stress reactivity and cognition in adult offspring

open access: yesStress, 2015
Human epidemiological studies have provided compelling evidence that prenatal exposure to stress is associated with significantly increased risks of developing psychiatric disorders in adulthood.
Yan-ying Zeng   +4 more
semanticscholar   +1 more source

Long-term effects of prenatal fluoride and lead exposure on educational delay in Mexico

open access: yesISEE Conference Abstracts, 2023
Jose Luis Figueroa   +8 more
openaire   +1 more source

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