Results 201 to 210 of about 63,552 (287)

Prenatal maternal stress in rats alters the epigenetic and transcriptomic landscape of the maternal-fetal interface across four generations. [PDF]

Commun Biol
King SE, Schatz NA, Babenko O, Ilnytskyy Y, Kovalchuk I, Metz GAS.   +5 more
europepmc   +1 more source

Healthcare Professionals' Perspectives on Barriers to Reproductive Care Access in One Urban City: A Qualitative Study

Research in Nursing &Health, EarlyView.
ABSTRACT Inequities exist in reproductive care access for biological women of childbearing age from minoritized, racialized, and lower socioeconomic communities in the United States. While patient‐reported barriers are well documented, less is known about healthcare providers' perceptions of these challenges in urban, under‐resourced contexts ...
Roxanne Mirabal‐Beltran, Erika Ventura Castellon, Laura Spagna, Kelly Zhang, Karyn J. Roberts   +4 more
wiley   +1 more source

Assessing Neighborhood Characteristics and Their Association with Prenatal Maternal Stress, Depressive Symptoms, and Well-Being in Eight Culturally Diverse Cities: A Cross-Sectional Study. [PDF]

Int J Environ Res Public Health
Campo-Tena L, Roman GD, Murray AL, Luong-Thanh BY, Marlow M, Anwer Y, Dadzie A, Foley S, Hernandez SS, Lindsay C, Randeny S, Smith JA, Taut D, Eisner MP.   +13 more
europepmc   +1 more source

Missed Nursing Care in Neonatal Intensive Care Units for Infants Experiencing or at Risk of Experiencing Substance Withdrawal

Research in Nursing &Health, EarlyView.
ABSTRACT Caring for infants experiencing or at risk of substance withdrawal often increases nursing workload and may contribute to missed nursing care (MNC). This study examined the relationship between infants' substance withdrawal status and the occurrence of MNC in neonatal intensive care units (NICUs). We conducted a secondary analysis of data from
Sooyoung Kim, Adam C. Carle, Rita Pickler, Jin Jun, Heather L. Tubbs‐Cooley   +4 more
wiley   +1 more source

Optical mapping reveals a higher level of large‐scale structural variants in a family with paternally transmitted myotonic dystrophy and independent Parkinson's disease

The Journal of Pathology, EarlyView.
Abstract Myotonic dystrophy type 1 (DM1) is a clinically challenging multisystem neuromuscular hereditary disorder, with generational increase in severity and earlier age at onset. It is caused by an unstable cytosine‐thymine‐guanine repeat expansion at the DMPK locus, accompanied by associated genetic and epigenetic modifications.
Md Mehedi Hasan, Jenna Craddock, Tingting Gong, Ruth J Lyons, Igor Stevanovski, Sanjog R Chintalaphani, Ira W Deveson, Weerachai Jaratlerdsiri, Kishore R Kumar, Vanessa M Hayes   +9 more
wiley   +1 more source

Prenatal Exome Sequencing Identifies Dual Maternal‐Fetal Diagnosis of HbF Mission Bay, a Novel HBG2 Variant Associated With Methemoglobinemia, Hypoxia and Hemolytic Anemia

Prenatal Diagnosis, EarlyView.
ABSTRACT Prenatal exome sequencing (ES) can establish rare genetic diagnoses in a fetus but may also lead to occult genetic diagnosis in a biological parent. We present a case of dual fetal and maternal diagnosis by prenatal ES, in a fetus with unexplained anemia and in a pregnant patient with sickle cell disease (SCD) and recurrent unexplained hypoxia.
Matthew A. Shear, Billie Lianoglou, Ugur Hodoglugil, W. Patrick Devine, Ashutosh Lal, Juan Gonzalez, Teresa N. Sparks   +6 more
wiley   +1 more source

Prenatal maternal stress and child hair cortisol four years later: Evidence from a low-income sample. [PDF]

Psychoneuroendocrinology, 2020
Alen NV, Hostinar CE, Mahrer NE, Martin SR, Guardino C, Shalowitz MU, Ramey SL, Schetter CD.   +7 more
europepmc   +1 more source

Hemophilia A: An Ideal Disease for Prenatal Therapy

Prenatal Diagnosis, EarlyView.
ABSTRACT Hemophilia A (HA) is the most common inherited coagulation defect. Current state‐of‐the‐art treatment consists of frequent administration of prophylactic infusions of coagulation factor VIII (FVIII) protein or bispecific antibodies that replace the cofactor function of FVIIIa to maintain hemostasis. However, these treatments are far from ideal,
Christopher D. Porada, Anthony Atala, Graça Almeida‐Porada   +2 more
wiley   +1 more source

Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis

Prenatal Diagnosis, EarlyView.
ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell, Samantha Stover, Nora Gibson, Timothy Olson, James Connelly, Matthew Grace, Jennifer Andrews   +6 more
wiley   +1 more source

Hemolytic Disease of the Fetus and Newborn: Fetal RHD Genotyping, Targeted Prophylaxis, and Prenatal Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Hemolytic disease of the fetus and newborn (HDFN) remains a significant concern in prenatal care primarily caused by maternal alloimmunization against fetal red blood cell antigens, most commonly the D antigen. Noninvasive fetal RHD genotyping, used as a screening tool, enables targeted antenatal prophylaxis and has been implemented in several
Emilie Thorup, Steffen Thorsen, Morten Hanefeld Dziegiel, Olav Bjørn Petersen, Frederik Banch Clausen   +4 more
wiley   +1 more source