Results 221 to 230 of about 63,552 (287)

Prenatal Screening for Common Aneuploidy in Southeast Asian Countries: A Systematic Review of Challenges and Opportunities

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Southeast Asian (SEA) countries face persistent challenges in equitable healthcare delivery. Given the high prevalence of aneuploidy, increasing use of advanced prenatal screening technologies, and challenges reported in other regions, this study aimed to identify and assess existing policies and guidelines as well as the enablers and barriers
Rapphon Sawaddisan   +3 more
wiley   +1 more source

Impact of Fetoscopic Surgery on the Myometrium: Experimental Study in an Ovine Model of Myelomeningocele

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective To investigate uterine healing at delivery after fetoscopic myelomeningocele (MMC) closure in an ovine model. Methods This descriptive study was conducted in Romane ewes. Fetal MMC lesions were created after hysterotomy at 75 days of gestation.
Enora Parc   +5 more
wiley   +1 more source

MRI in Sheep Model for Myelomeningocele Repair Using a Novel Polymer and Other Dural Patches

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective To compare postnatal MRI outcomes after prenatal myelomeningocele repair using three different dural substitutes. Method 32 sheep fetuses were included, with 34.3%(11/32) serving as healthy controls and the remaining undergoing prenatal spinal lumbar defect creation to recreate a myelomeningocele in the fetus.
Usha D. Nagaraj   +5 more
wiley   +1 more source

Middle Cerebral Artery Doppler and Cerebroplacental Ratio Predict Adverse Neurological Outcomes in Fetal Growth Restriction

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective To assess the efficacy of middle cerebral artery (MCA) Doppler ultrasonography in predicting neurological and respiratory outcomes in fetuses with fetal growth restriction (FGR) and to establish a correlation between MCA Doppler and head circumference (HC). Method Retrospective cohort study examining singleton pregnancies affected by
Silvia Visentin   +6 more
wiley   +1 more source

Is There Potential Clinical Utility in Reporting Variants of Uncertain Significance From Prenatal Sequencing?

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective Prenatal sequencing of fetuses with abnormalities detected on imaging is expanding globally. Debate continues over whether variants of uncertain significance (VUS) should be reported prenatally, with some recent national position statements opposing this.
A. Gibbs   +13 more
wiley   +1 more source

Placental Dysfunction and Congenital Heart Disease: Investigating the Placenta‐Heart Axis

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective Concurrent development of the placenta and heart during early gestation suggests a shared biological basis for the co‐occurrence of abnormal placentation and congenital heart disease (CHD). This study investigated the association between placental vascular pathology and CHD type.
Natalie Lanners   +10 more
wiley   +1 more source

Prenatal Spectrum of COL2A1‐Related Spondyloepiphyseal Dysplasia Congenita: A Review and Two Case Reports

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective To review the published literature on prenatal findings of COL2A1‐related SEDC, summarizing reported imaging and molecular variants, and to describe two additional prenatal cases evaluated at a tertiary referral center. Method A narrative review with a systematic search strategy was conducted to analyze prenatal imaging findings ...
López‐Rodríguez Larissa   +10 more
wiley   +1 more source

Fetal Brain Abnormalities Following Laser Surgery for Twin‐to‐Twin Transfusion Syndrome: Imaging Patterns and Evolution

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Introduction Severe brain injury has been reported following fetoscopic laser ablation (FLA) for twin‐to‐twin transfusion syndrome (TTTS), but imaging patterns and temporal evolution remain poorly defined. This study aimed to characterize the progression of severe brain injury after FLA. Methods We conducted a retrospective case series of TTTS
Yada Kunpalin   +8 more
wiley   +1 more source

Performance of a Flexible Versus Rigid Fetoscope in the Simulated Management of Twin‐to‐Twin Transfusion Syndrome

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objective To assess the feasibility and operative performance of a flexible fetoscope (FF) compared with a rigid fetoscope (RF) in the simulated management of twin‐to‐twin transfusion syndrome (TTTS) with anterior placentation. Method A randomized, non‐blinded crossover trial was conducted during a national training session for fetal surgeons.
Emmanuel Rault   +5 more
wiley   +1 more source

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