Results 91 to 100 of about 5,219,314 (384)

Phase II trial of preoperative radiochemotherapy with concurrent bevacizumab, capecitabine and oxaliplatin in patients with locally advanced rectal cancer [PDF]

, 2013
Background: Preoperative radiochemotherapy (RCT) with 5-FU or capecitabine is the standard of care for patients with locally advanced rectal cancer (LARC). Preoperative RCT achieves pathological complete response rates (pCR) of 10-15%.
Arnold, Dirk, Dellas, Kathrin, Dunst, Jürgen, Engel, Erik, Höhler, Thomas, Reese, Thomas, Richter, Michael, Rödel, Claus, Wagner, Wolfgang, Würschmidt, Florian   +9 more
core   +1 more source

The Evolutionary Trajectory and Prognostic Value of GITR+ Tregs Reprogramed by Tumor‐Intrinsic PD‐1/c‐MET Signaling in Pancreatic Cancer

Advanced Science, EarlyView.
In pancreatic ductal adenocarcinoma (PDAC), tumor‐intrinsic PD‐1 signaling activates the MET pathway, leading to the establishment of an immunosuppressive tumor microenvironment (TME). This MET‐driven signaling cascade promotes the selective accumulation of GITR+ regulatory T cells (Tregs), a highly immunosuppressive subset.
Jiande Han, Hanlin Yin, Taochen He, Junyi He, Zhenlai Jiang, Qiangda Chen, Zhihang Xu, Yuqi Xie, Yaolin Xu, Haibo Wang, Wenquan Wang, Wenchuan Wu, Yun Jin, Wenhui Lou, Jun Yu, Ning Pu, Liang Liu   +16 more
wiley   +1 more source

A 5-year observational study of cancellations in the operating room: Does the introduction of preoperative preparation have an impact?

Saudi Journal of Anaesthesia, 2014
Background: Preoperative preparation (assessment) of patients reduces cancellations on the day of surgery. A Center for Reviews and Dissemination review (2007) concluded "the evidence was weak and it was uncertain that preassessment reduced cancellations.
Douglas R. A. McKendrick, Grant P Cumming, Amanda J Lee   +2 more
doaj   +1 more source

Does Preoperative Ostomy Education Decrease Anxiety in the New Ostomy Patient? [PDF]

, 2019
Background: There are approximately 100,000 patients with new ileostomies and colostomies created in the United States each year. These patients have specialized needs that include acceptance of altered body image, psychological stress, learning of ...
Harris, Michelle Suzann
core   +1 more source

Midwives’ Adherence to Preoperative Care Guidelines Prior to Emergency Caesarean Section at Bwaila Maternity Hospital in Malawi

, 2014
A study was conducted to describe midwives' adherence to preoperative care during emergency caesarian section at Bwaila Maternity Wing in 2012 in Malawi. The study utilized a descriptive prospective and retrospective design.
Ruth Mwale, A. Maluwa, A. Malata, J. Odland   +3 more
semanticscholar   +1 more source

PIEZO1‐GPX4 Axis Mediates Mechanical Stress‐Induced Vertebral Growth Plate Dysplasia via Ferroptosis Activation

Advanced Science, EarlyView.
Mechanical stress activates PIEZO1 in vertebral growth plate chondrocytes, triggering ferroptosis through direct binding and inhibition of GPX4. This axis promotes lipid peroxidation and pathological ossification, accelerating spinal deformities. Clinical and genetic evidence (Piezo1‐cKO) confirms its role in scoliosis progression.
Fei Chen, Fushuai Peng, Shuqing Chen, Yukun Du, Jianyi Li, Yuanyuan Fan, Zichen Cui, Guanghui Gu, Han Zhang, Zhensong Jiang, Guodong Wang, Xingzhi Jing, Jun Dong, Tao Li, Yongming Xi   +14 more
wiley   +1 more source

Impact of surgical treatment of benign prostate hyperplasia on lower urinary tract symptoms and quality of life [PDF]

Vojnosanitetski Pregled, 2019
Background/Aim. Benign prostatic hyperplasia (BPH) is a pathological process, which is one of the most common causes of so-called lower urinary tract symptoms (LUTS).
Babić Uroš, Soldatović Ivan, Vuković Ivan, Dragićević Svetomir, Đorđević Dejan, Aćimović Miodrag, Šantrić Veljko, Džamić Zoran, Vuksanović Aleksandar   +8 more
doaj   +1 more source

The effect of preoperative stoma site marking on quality of life in patients undergoing ostomy surgery [PDF]

, 2008
The purpose of this study was to determine if preoperative stoma site marking by a Wound, Ostomy, Continence (WOC) nurse affects patient quality of life. This study used a descriptive design with a convenience sample of 25 ostomy patients.
Cantara, Susan L
core   +2 more sources

Early and Late Reoperation Rates With Various MIS Techniques for Adult Spinal Deformity Correction. [PDF]

, 2018
Study designA multicenter retrospective review of an adult spinal deformity database.ObjectiveWe aimed to characterize reoperation rates and etiologies of adult spinal deformity surgery with circumferential minimally invasive surgery (cMIS) and hybrid ...
Akbarnia, Behrooz A, Anand, Neel, Chou, Dean, Deviren, Vedat, Eastlack, Robert K, International Spine Study Group, Kanter, Adam S, Mummaneni, Praveen V, Mundis, Gregory M, Nguyen, Stacie, Nunley, Pierce, Okonkwo, David O, Park, Paul, Srinivas, Ravi, Uribe, Juan S   +14 more
core   +1 more source

Preoperative Multimodal Analgesia Decreases Postanesthesia Care Unit Narcotic Use and Pain Scores in Outpatient Breast Surgery

Plastic and Reconstructive Surgery, 2018
Background: The opioid epidemic demands changes in perioperative pain management. Of the 33,000 deaths attributable to opioid overdose in 2015, half received prescription opioids.
Jenny C. Barker, Kaitlin K DiBartola, Corinne E. Wee, N. Andonian, M. Abdel-Rasoul, Deborah S. Lowery, J. Janis   +6 more
semanticscholar   +1 more source