Results 121 to 130 of about 5,340,979 (387)

Radio-chemotherapy as a preoperative treatment for advanced rectal cancer. Evaluation of down-staging and morbidity [PDF]

, 2002
Background: The standard therapy for patients with clinically resectable rectal cancer is generally considered to be surgery, If the patient is diagnosed with advanced disease, postoperative radiochemotherapy (RCT) is usually recommended. In our study we
Dühmke, Eckhart, Schaffer, Moshe, Schaffer, Pamela Manuela, Thoma, M., Wilkowski, R.   +4 more
core   +1 more source

Aloe‐Emodin Targeting FOXC2 Disrupts NETs Formation and EMT‐Driven Postoperative Peritoneal Adhesion Through TGF‐β1‐Smad2/3 Pathway

Advanced Science, EarlyView.
Forkhead box protein C2 (FOXC2) is highlighted as a pivotal effector in postoperative peritoneal adhesion (PPA) formation. Mechanically, FOXC2 mediates NETs‐induced EMT alterations through the TGF‐β1‐Smad2/3 pathway. Aloe‐emodin (AE) ameliorates FOXC2‐driven fibrosis by blocking NETs formation and EMT changes through this pathway.
Lili Yang, Yunda Fang, Yuheng Lian, Ziyang Kong, Jia Miao, Yanqi Chen, Wen Li, Feiyan Chen, Bin Zhang, Yao Chen, Yaoyao Bian   +10 more
wiley   +1 more source

Using Peripheral Venous Pressure Waveforms to Predict Key Hemodynamic Parameters [PDF]

, 2019
Analysis of peripheral venous pressure (PVP) waveforms is a novel method of monitoring intravascular volume. Two cohorts were used to study the hemodynamics change of the body state and its influence on the PVP using (1) dehydration setting with infants ...
AlAlawi, Ali Zohair A
core   +2 more sources

Laeverin is Cell‐Surface Target for Liquid‐Phase Metastasizing Cancer Cells

Advanced Science, EarlyView.
This study revealed that epithelial cancer cells in the floating phase induce the expression of laeverin (LVRN) that is a trophoblast‐specific and cell‐surface immunoregulatory factor and showed that anti‐LVRN ADC is a promising agent that can attack cancer cells in the metastatic liquid phase and block further distant metastasis.
Haruki Kasama, Yuya Sakai, Kyosuke Kagami, Takashi Iizuka, Tatsuhito Kanda, Takuma Suzuki, Kayo Kayahashi, Masanori Ono, Tomoko Fujiwara, Shintaro Yagi, Noriyuki Inaki, Isao Matsumoto, Rena Yamazaki, Kaoru Abiko, Noriomi Matsumura, Akira Hattori, Takiko Daikoku, Hiroshi Fujiwara   +17 more
wiley   +1 more source

Preoperative assessment of adults undergoing elective noncardiac surgery

European Journal of Anaesthesiology
BACKGROUND When considering whether a patient is fit for surgery, a comprehensive patient assessment represents the first step for an anaesthetist to evaluate the risks associated with the procedure and the patient's underlying diseases, and to optimise (
Massimo Lamperti, Carolina S. Romero, Fabio Guarracino, G. Cammarota, L. Vetrugno, B. Tufegdzic, Francisco Lozsan, Juan Jose Macias Frias, Andreas Duma, Matthias Bock, Kurt Ruetzler, Silvia Mulero, Daniel A. Reuter, L. La Via, Simon Rauch, Massimiliano Sorbello, Arash Afshari   +16 more
semanticscholar   +1 more source

Cytological Classification Diagnosis for Thyroid Nodules via Multimodal Model Deep Learning

Advanced Science, EarlyView.
This study introduces AI‐TFNA, an innovative artificial intelligence model designed to assist cytopathologists in classifying thyroid nodules based on The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC). The model effectively differentiates between benign and malignant thyroid nodules, demonstrating significant potential as a screening ...
Yuanzheng Lou, Yongjian Su, Haoda Lu, Wencai Li, Weihua Yin, Shengnan Li, Huobiao Zhu, Kok Haur Ong, Gang Chen, Yong Jiang, Yifei Liu, Shenglei Li, Manchun Yang, Zhengyu Zhang, Xiaoyan Wang, Xiaohui Zhu, Xinmi Huo, Longjie Li, Chao Wang, Nanyan Zhang, Weijun Pan, Bin Shang, Xudan Yang, Yongqiang Zhu, Xiaolin Liu, Weimiao Yu, Xiuwu Bian, Yanqing Ding   +27 more
wiley   +1 more source

Predicting Acetabular Component Size in Bipolar Hip Hemiarthroplasty Using Digital Radiographs: A Prospective Study on Accuracy

Journal of Clinical and Diagnostic Research
Introduction: Elderly individuals frequently suffer from hip fractures, particularly femoral neck intracapsular fractures, which can cause serious morbidity.
Umesh Samria, Naveen Sathiyaseelan, Akib Nisar Sheikh, Pankaj Jain, Pradeep Khinchi   +4 more
doaj   +1 more source

Preoperative predictors of postoperative aspiration risk after cardiac surgery

Research in Cardiovascular Medicine, 2017
Background: Aspiration is a common complication among hospitalized patients, and patients undergoing cardiac surgery are at increased risk. Our aim was to determine if screening for frailty could identify patients at risk for aspiration.
B Jason Bowles, Jo Puntil-Sheltman, Dallas Mullins, Katie M Craig, Jose Benuzillo   +4 more
doaj   +1 more source

Management of hospital admission, patient information and education, and immediate preoperative care. [PDF]

Saudi J Anaesth, 2023
Greco M, Calgaro G, Cecconi M.
europepmc   +1 more source

Engineered Multifunctional Hydrogel Delivering Novel CBX7 Inhibitor Modulates Cuproptosis Via Liquid–Liquid Phase Separation to Restore Cardiac Function in Aged Myocardial Infarction

Advanced Science, EarlyView.
An age‐adapted therapy pairs δ‐Amyrenone, a CBX7 inhibitor, with an alginate hydrogel (CSAδ) to rescue infarcted elderly hearts. CSAδ disrupts CBX7–ATP7A liquid–liquid phase separation, restores ATP7A trafficking and copper efflux, suppresses cuproptosis, supplies oxygen, scavenges ROS, promotes M2 polarization, supports angiogenesis, and enhances ...
Jun Liu, Peng Qu, Jiao Shi, Tingting Liang, Yao Gu, Xue Li, Cui Ma, Danyang Zhao, Feila Liu, Qi Liang, Panke Cheng, Qian Lei   +11 more
wiley   +1 more source