Results 261 to 270 of about 647,081 (351)

The influence of stigma on PrEP uptake among adolescent girls and young women in Johannesburg, South Africa and Mwanza, Tanzania: Qualitative findings from the EMPOWER study. [PDF]

PLoS One
Stangl AL, Bryan C, Barré I, Ramskin L, Lees S, Ndimande-Khoza N, Baron D, Colombini M, Harvey S, Kapiga S, Scorgie F, Delany-Moretlwe S.   +11 more
europepmc   +1 more source

KMT2C Loss Promotes NF2‐Wildtype Meningioma Progression and Ferroptosis Sensitivity via Epigenetic Repression of Hippo Signaling

Advanced Science, EarlyView.
In NF2–wild‐type meningiomas, loss of the epigenetic regulator KMT2C suppresses NF2 transcription and inactivates Hippo signaling, driving tumor progression and increasing ferroptosis sensitivity. Restoration of histone acetylation reverses these effects and inhibits tumor growth, identifying KMT2C as a key regulator linking epigenetic control, NF2 ...
Liuchao Zhang, Yangfan Ye, Wei Gu, Xinyue Wang, Nuo Chen, Qixin He, Lei Xu, Pengzhan Zhao, Guoqiang Fu, Guangyao Yuan, Wenqian Shi, Honglu Chao, Yiming Tu, Jing Ji   +13 more
wiley   +1 more source

College Pliny and Vergil. Latin Text with Facing Vocabulary and Commentary (G.) Steadman Pp. 170, ills. Independently published, 2023. Paper, £8.04. ISBN: 979-8987488416. https://geoffreysteadman.com/ap-pliny-and-vergil/

The Journal of Classics Teaching
Brian James Zawiski
doaj   +1 more source

"It would have been easier for me to give up if I were alone": how a pilot individualized case management intervention influenced female sex workers' oral HIV pre-exposure prophylaxis use in eThekwini, South Africa. [PDF]

BMC Public Health
Rock A, Shoen M, Shipp L, Mulumba N, Ryan S, Makama S, Mcingana M, Comins C, Hausler H, Baral S, Schwartz S.   +10 more
europepmc   +1 more source

SAA/FPR2 Signaling Between Pericentral Hepatocytes and Macrophages Exacerbates Zonated Liver Transplant Injury

Advanced Science, EarlyView.
After liver transplantation, ischemia‐reperfusion injury is more severe in pericentral regions. Multiomic analyses of human grafts and mouse models identify FOXO1 activation in pericentral hepatocytes as an upstream driver of SAA secretion. SAA recruits and activates FPR2+ macrophages, amplifying local inflammation. Amilo‐5MER inhibits SAA bioactivity,
Feng Zhang, Rong Li, Tingting Wang, Jianhao Zhang, Zhengqi Wu, Qiang You, Xuying Liu, Cuicui Xiao, Jiebin Zhang, Haitian Chen, Jiaqi Xiao, Jia Yao, Jun Zheng, Yingcai Zhang, Hua Li, Shuhong Yi, Yang Yang, Qi Zhang, Xiaofeng Yuan, Yasong Liu   +19 more
wiley   +1 more source

A Tiered Latin Reader (A.C.) Pisarello Cicero: Pro Archia Poeta Oratio. Pp. xxviii + 173. Pixelia Publishing, 2024. Paper, US$9.99. ISBN: 9781737033066. https://pixeliapublishing.org/cicero-pro-archia-poeta-oratio/

The Journal of Classics Teaching
Brian James Zawiski
doaj   +1 more source

GPX4 Inhibitor Resistance and Metastatic Features in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study establishes breast cancer cell lines that are resistant to glutathione peroxidase 4 inhibitors (GPX4i) in vitro and investigates the metastatic capacity of the GPX4i‐resistant versus parental lines in vivo. GPX4i‐resistant cells survive upon intravenous injection, but lose capacity to spontaneously metastasize.
Marie Sabatier, Mayher Kaur, Milena Chaufan, Felix‐Levin Hormann, Luiza Martins Nascentes Melo, Mario Palma, Jordan Torpey, Yanshan Liang, Alanis Carmona, Cameron Fraser, Midori Flores, Krystina J. Szylo, Mahsa Yavari, Sheng Hui, Alpaslan Tasdogan, Sven Heiles, Jessalyn M. Ubellacker   +16 more
wiley   +1 more source

Echolands; A Journey in Search of Boudica (D.) Mackay, Pp. xx + 346, map, b/w & colour pls. London: Hodder & Stoughton, 2023. Cased, £25. ISBN: 9781399714112

The Journal of Classics Teaching
Brian J. Zawiski
doaj   +1 more source

A web of risk: multilevel factors and feedback loops (re)produce HIV 'risk' among gay, bisexual and other men who have sex with men - a global systematic review. [PDF]

J Epidemiol Community Health
Stojanovski K, Ogarrio K, Kubat E, King EJ, Theall KP, Geronimus AT.   +5 more
europepmc   +1 more source

FomA‐Containing Outer Membrane Vesicles of Fusobacterium Nucleatum Facilitate Bladder Cancer Lymphatic Metastasis via IL‐6‐Dependent M2b Macrophage Polarization

Advanced Science, EarlyView.
Urinary Fusobacterium nucleatum–derived outer membrane vesicles are shown to promote bladder cancer lymphatic metastasis. The vesicle protein FomA activates TLR2/NF‐κB signaling in tumor cells, induces IL‐6 secretion, and drives M2b macrophage polarization and VEGF‐C–dependent lymphangiogenesis, revealing a microbiota‐driven mechanism linking tumor ...
Wentai Shangguan, Weijia Li, Wenxue Huang, Jilin Wu, Yao Yu, Yiyao Huang, Lin Yang, Ming Xie, Qishen Yang, Jun Zheng, Yuexuan Zhu, Qi Sun, Biao Li, Leqian Li, Zongwei Wang, Jie Zhao, Peng Wu, Bisheng Cheng   +17 more
wiley   +1 more source