Analytical Life Cycle Assessment as a 10-Stage Framework for Evaluating and Improving the Sustainability of Analytical Workflows. [PDF]
Anal ChemMansour FR +4 more
europepmc +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Comparison of Microtensile Bond Strengths of Giomers Using HEMA-Based and HEMA-Free Silane Adhesive With Laser-Cut and Bur-Cut Dentin. [PDF]
Int J DentTaha RROO, Ibrahim AH, Ibrahim SH.
europepmc +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Preparing Therapy Dogs for Animal-Assisted Services: Governance, Welfare-Centred Preparation, and a Lifecycle Research Agenda Across Selected European and United States Frameworks. [PDF]
Animals (Basel)Shajid Pyari M, Guo K, Kargas N.
europepmc +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
The Impact of a Dental Technology Curriculum and a Preventive-Clinical Curriculum on the Development of Preclinical Preparation Skills. [PDF]
Dent J (Basel)Morlock L +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Green, one-pot strategy for substitution of the 5-position of 1,10-phenanthrolines. [PDF]
RSC AdvWheeler JP +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source