ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown +6 more
wiley +1 more source
Identification and Structural Elucidation of Galloylated B-Type Procyanidins From Rumex obtusifolius L. Using Enzymatic Digestion, Phloroglucinolysis, and High-Resolution Mass Spectrometry. [PDF]
Ballert S +5 more
europepmc +1 more source
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source
FDG‐PET Associations With Disease Severity and Outcomes in NMDA‐Receptor IgG Autoimmune Encephalitis
ABSTRACT Background Patients with N‐methyl‐D‐aspartate (NMDA) receptor‐immunoglobulin G (IgG) autoimmune encephalitis (NMDAR‐IgG AE) demonstrate occipital lobe hypometabolism on baseline brain fluorodeoxyglucose‐positron emission tomography (bFDG‐PET).
Jonathan K. Lee +7 more
wiley +1 more source
Unambiguous analytical separation and improved syntheses of [11C]acetate and [11C]acetoacetate. [PDF]
Bamminger K +4 more
europepmc +1 more source
Synthesis, Properties, and Enantioseparation of Four-Ring Racemic Smectics. [PDF]
Wojda E +3 more
europepmc +1 more source
Automated radiosynthesis of 2-[<sup>18</sup>F]BPA for PET-based planning of boron neutron capture therapy (BNCT): rational precursor design, radiofluorination, and characterization of methodology. [PDF]
Paolillo V +4 more
europepmc +1 more source
Optimization and scale up strategies for reproducible AAV enrichment step on CIMmultus<sup>®</sup> QA HR line. [PDF]
Žigon R +6 more
europepmc +1 more source
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