Results 21 to 30 of about 249,708 (256)

Establishing National Multisectoral Coordination and collaboration mechanisms to prevent, detect, and respond to public health threats in Guinea, Liberia, and Sierra Leone 2016–2018

One Health Outlook, 2019
Background The governments of Guinea, Liberia, and Sierra Leone have acknowledged that weak health systems and poor coordination of efforts hampered effectiveness of the 2014–2016 Ebola outbreak response.
Serge Agbo, Lionel Gbaguidi, Chethana Biliyar, Seydou Sylla, Mukeh Fahnbulleh, John Dogba, Sakoba Keita, Sarian Kamara, Amara Jambai, Albert Harris, Tolbert Nyenswah, Mane Seni, Sow Bhoye, Sambe Duale, Andrew Kitua   +14 more
doaj   +1 more source

Bridging the humanitarian-development divide in a protracted crisis: a case study of the use of a central plant to supply oxygen for COVID-19 case management in South Sudan

Frontiers in Public Health, 2023
The rising demand for medicinal oxygen due to the COVID-19 pandemic exacerbated an underlying chronic shortage of the commodity in Africa. This situation is particularly dire in protracted crises where insecurity, dysfunctional health facilities, poor ...
Olushayo Oluseun Olu, Alex Yao Sokemawu Freeman, Joy Luba Lomole Waya, Argata Guracha Guyo, Benedict Kanu, Michael Tukuru, Sylvester Maleghemi   +6 more
doaj   +1 more source

Evaluation of the pilot wastewater surveillance for SARS-CoV-2 in Norway, June 2022 – March 2023

BMC Public Health, 2023
Background During the COVID-19 pandemic, wastewater-based surveillance gained great international interest as an additional tool to monitor SARS-CoV-2.
Ettore Amato, Susanne Hyllestad, Petter Heradstveit, Petter Langlete, Line Victoria Moen, Andreas Rohringer, João Pires, Jose Antonio Baz Lomba, Karoline Bragstad, Siri Laura Feruglio, Preben Aavitsland, Elisabeth Henie Madslien   +11 more
doaj   +1 more source

Rapid diagnostic test: a critical need for outbreak preparedness and response for high priority pathogens

BMJ Global Health
Rapid diagnostic tests (RDTs) are critical for preparedness and response against an outbreak or pandemic and have been highlighted in the 100 Days Mission, a global initiative that aims to prepare the world for the next epidemic/pandemic by driving the ...
Paul A Kristiansen, Solomon Abebe Yimer, Birgitte Boonstra Booij, Gwen Tobert, Andrew Hebbeler, Paul Oloo, Polina Brangel, Maïna L'Azou Jackson, Richard Jarman, Danielle Craig, Michael Selorm Avumegah, Henshaw Mandi, Timothy Endy, Stacey Wooden, Carolyn Clark, Valentina Bernasconi, Amy Shurtleff   +16 more
doaj   +1 more source

Australian Culex annulirostris mosquitoes are competent vectors for Japanese encephalitis virus genotype IV

Emerging Microbes and Infections
Japanese encephalitis virus (JEV) is transmitted by Culex species of mosquitoes. In 2022, JEV belonging to a previously unrecognized lineage of genotype IV (GIV) caused a major outbreak of JE in South-eastern Australia, resulting in human cases and ...
Melissa J. Klein, Sarah A. Jackson, Willy W. Suen, Jean Payne, Darcy Beveridge, Mel Hargreaves, Donna Gillies, Jianning Wang, Kim R. Blasdell, Mike Dunn, Adam J. López-Denman, Peter A. Durr, David T. Williams, Prasad N. Paradkar   +13 more
doaj   +1 more source

Optical microscopy reveals the dynamic nature of B. pseudomallei morphology during β-lactam antimicrobial susceptibility testing

BMC Microbiology, 2020
Background In Gram-negative species, β-lactam antibiotics target penicillin binding proteins (PBPs) resulting in morphological alterations of bacterial cells.
Heather P. McLaughlin, Julia Bugrysheva, David Sue   +2 more
doaj   +1 more source

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo, Shehu Umar Abdullahi, Hassan Adam Murtala, Halima Kabir, Khadija A. Shamsu, Sari A. Acra, Virginia A. Stallings, Mark Rodeghier, Michael R. DeBaun, Lauren J. Klein   +9 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Considerations for bioanalytical characterization and batch release of COVID-19 vaccines

npj Vaccines, 2021
The COVID-19 pandemic has prompted hundreds of laboratories around the world to employ traditional as well as novel technologies to develop vaccines against SARS-CoV-2. The hallmarks of a successful vaccine are safety and efficacy.
Gautam Sanyal, Anna Särnefält, Arun Kumar   +2 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source