Results 31 to 40 of about 499,740 (281)
Race and Income Disparities in Disaster Preparedness in Old Age [PDF]
, 2017 Objective: Older adults are one of the most vulnerable populations impacted by disasters and communities continue to struggle addressing preparedness.
Cox, Katherine M.
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Considerations for bioanalytical characterization and batch release of COVID-19 vaccines
npj Vaccines, 2021 The COVID-19 pandemic has prompted hundreds of laboratories around the world to employ traditional as well as novel technologies to develop vaccines against SARS-CoV-2. The hallmarks of a successful vaccine are safety and efficacy.
Gautam Sanyal +2 more
doaj +1 more source
Evaluation of a School Based Disaster Preparedness Program [PDF]
, 2006 This study evaluated a school based intervention designed to better prepare teachers and staff members in an elementary school to improve their knowledge and confidence of disaster preparedness.
Linebarger, Sandra
core +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
BMC Microbiology, 2020 Background In Gram-negative species, β-lactam antibiotics target penicillin binding proteins (PBPs) resulting in morphological alterations of bacterial cells.
Heather P. McLaughlin +2 more
doaj +1 more source
Strategies for supplying face masks to the population of Taiwan during the COVID-19 pandemic
BMC Public Health, 2021 Background The use of face masks has become ubiquitous in Taiwan during the early COVID-19 pandemic. A name-based rationing system was established to enable the population of Taiwan to purchase face masks.
Chin-Mei Liu +6 more
doaj +1 more source
BMJ Global Health, 2023 The WHO Regional Office for Africa (AFRO) COVID-19 Incident Management Support Team (IMST) was first established on 21 January 2020 to coordinate the response to the pandemic in line with the Emergency Response Framework and has undergone three ...
Thierno Balde +12 more
doaj +1 more source
Emergency preparedness and response in New Zealand schools : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Emergency Management at Massey University, Wellington, New Zealand [PDF]
, 2017 International disaster risk reduction efforts prioritise school safety. Providing a safe learning environment for students and ensuring their continued access to education after an emergency has a positive influence on student, family, and community ...
Tipler, Karlene Susan
core
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source