Results 101 to 110 of about 698,564 (286)

Improving genetic diagnosis of hereditary tumor syndromes: From expanded gene panels to functional genomics

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Genetic tumor risk syndromes (genturis) contribute substantially to the overall cancer burden and provide opportunities for early detection, prevention, and individualized treatment. Yet, many affected individuals remain undiagnosed due to restrictive testing criteria and challenges in variant interpretation.
Mayra Sauer   +11 more
wiley   +1 more source

Popular options for preprints. [PDF]

open access: yes, 2013
Free: Can preprints be submitted for free. Comments: Support for online comments. Private: Support for private preprints. Peer-Reviewed: Whether the preprints are peer-reviewed on the server. DOI: Each item is assigned a unique digital object identifier.
Joel J. Adamson (585381)   +5 more
core   +1 more source

Epigenetic Dysregulation of Somatostatin Receptors (SSTR) 1–5 and Therapeutic Implications in Neuroendocrine and Non‐Neuroendocrine Malignancies

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Somatostatin receptors (SSTR) mediate the antiproliferative, antisecretory, and proapoptotic effects of somatostatin and its synthetic analogs. Their surface expression on neuroendocrine tumor (NET) cells is required for somatostatin analog therapy and radiopharmaceutical therapy (RPT).
Neeraj Kumari   +10 more
wiley   +1 more source

REMA Preprints [PDF]

open access: yes
Temporary project for uploading REMA preprints to ...
David Jonas Fisher
core  

Antarctic soil microbiomes encode structurally conserved and phylogenetically diverse beta‐lactamases

open access: yesiMetaOmics, EarlyView.
An integrative metagenomic framework combining sequence, structural, and functional inference reveals a phylogenetically diverse and structurally conserved repertoire of putative beta‐lactamases across Antarctic soil microbiomes, with predominance of class A and subclass B3 enzymes and limited but detectable associations with mobile genetic elements ...
José Coche‐Miranda   +8 more
wiley   +1 more source

Body, Emotions, and Hormones: A Systematic Review of Body Dissatisfaction, Emotion Regulation, and Puberty in Adolescence

open access: yesJournal of Adolescence, EarlyView.
ABSTRACT Objective Body dissatisfaction often arises from a discrepancy between perceived and ideal body images, posing a risk for psychological issues like depression and eating pathologies, particularly during adolescence. Puberty's rapid physical changes may exacerbate the feeling of dissatisfaction, additionally pubertal changes also influence ...
Isabella Muscolino   +3 more
wiley   +1 more source

Sense of Coherence in the Perinatal Period: A Longitudinal Growth Mixture Modeling Analysis

open access: yesJournal of Clinical Psychology, EarlyView.
ABSTRACT Objectives Previous studies have established that higher Sense of Coherence (SoC) predicts lower pregnancy‐specific distress, fewer delivery complications, and increased birth satisfaction. However, less is known about how SoC typically changes over pregnancy, birth, and postnatally and the risk factors and protective factors contributing to ...
Kelsey Perrykkad   +4 more
wiley   +1 more source

4. Programme Papers and Preprints [PDF]

open access: yes
This component contains preprints, working papers, and supporting manuscripts associated with the research programme The Coherence Problem: How Institutions Learn, Drift, and Realign.
'Robin Edgard Ulrik Mertens'
core  

Commentary: Making Patient Data Count—Opportunities and Challenges for Open Science in Clinical Psychology

open access: yesJournal of Clinical Psychology, EarlyView.
ABSTRACT Open science practices—such as preregistration, data and material sharing, and open‐access dissemination—are increasingly promoted across psychology, yet their specific value for clinical psychology has often been overlooked. This commentary argues that open science is particularly crucial for clinical psychology, where studies rely on small ...
Jan C. Cwik   +15 more
wiley   +1 more source

Sequelae of child maltreatment: Umbrella synthesis of 148 meta‐analyses on the mental health correlates

open access: yesJCPP Advances, EarlyView.
Our umbrella synthesis found strong, often equivalent, associations between child maltreatment and all examined mental health difficulties. Different types of maltreatment appear to have comparably negative effects on mental health. If replicated, these findings may cause us to reconsider conventional wisdom that suggests some forms of CM are less ...
Barry Coughlan   +7 more
wiley   +1 more source

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