Results 51 to 60 of about 341,268 (305)

Cluster randomised trial in the General Practice Research Database: 1. Electronic decision support to reduce antibiotic prescribing in primary care (eCRT study) [PDF]

, 2011
Background: the purpose of this research is to develop and evaluate methods for conducting cluster randomised trials in a primary care database that contains electronic patient records for large numbers of family practices.
Little Paul, Van Staa, Tjeerd; id_orcid, Ashworth, Maek, Delaney, Brendan, van Staa, Tjeerd, Gulliford Martin C, Moore Michael V, Judith Charlton, Paul Little, Gerard McCann, Gulliford, Martin C., Charlton, Judith, Little, Paul, Grieve, Andrew P, Ashworth Mark, Ashworth, Mark, Martin C Gulliford, Grieve Andrew P, Grieve, Andrew P., Van Staa, Tjeerd P., Dregan Alex, McCann, Gerard, Charlton Judith, electronic Cluster Randomised Trial Research Team eCRT Research, Taweel, Adel, Moore, Michael, Andrew P Grieve, Lucy Yardley, Mark Ashworth, Michael V Moore, Dregan, Alex; id_orcid, McCann Gerard, Tjeerd van Staa, Dregan, Alex, Yardley, Lucy, McDermott, Lisa, van Staa Tjeerd, null null, Electronic Cluster Randomised Trial Research Team eCRT Research Team, Wolfe, Charles, Lisa McDermott, Yardley Lucy, Gulliford, Martin C, Rudd, Anthony, Moore, Michael V, McDermott Lisa, Alex Dregan, Moore, Michael V.   +47 more
core   +2 more sources

The Use of Off-Label Medications in Newborn Infants Despite an Approved Alternative Being Available—Results of a National Survey

Pharmacy, 2022
Neonates continue to be treated with off-label or unlicensed drugs while in hospital. However, some medications that have previously been used in adults underwent clinical testing and licensure for use with a different indication in the neonatal and ...
Alex Veldman, Eva Richter, Christian Hacker, Doris Fischer   +3 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Knowledge, Attitudes and Perceptions of Medical Students on Antimicrobial Stewardship

Antibiotics, 2020
Antimicrobial Resistance (AMR) is an ongoing threat to modern medicine throughout the world. The World Health Organisation has emphasized the importance of adequate and effective training of medical students in wise prescribing of antibiotics Furthermore,
Panagiotis Efthymiou, Despoina Gkentzi, Gabriel Dimitriou   +2 more
doaj   +1 more source

Impact of the COVID-19 Pandemic on the Prescribing Patterns of First-Line Antibiotics in English Primary Care: A Longitudinal Analysis of National Prescribing Dataset

Antibiotics, 2021
The COVID-19 pandemic has impacted on public access to health services. This study aimed to investigate the impact of COVID-19 pandemic on commonly prescribed first-line antibiotics in English primary care.
Alisha Zubair Hussain, Vibhu Paudyal, Muhammad Abdul Hadi   +2 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Holistic health and social care outreach for people experiencing homelessness with recent non-fatal overdose in Glasgow, Scotland: the Pharmacist and third sector Homeless charity worker Outreach Engagement Non-medical Independent prescriber Rx (PHOENIx) pilot randomised controlled trial

BMJ Public Health
Objectives To examine randomised controlled trial (RCT) progression criteria including emergency department (ED) attendance and non-fatal overdose, from a holistic, integrated health and social care outreach intervention (PHOENIx), for people ...
Vibhu Paudyal, Nicola Greenlaw, Frances S Mair, Kate Stock, Andrew McPherson, Andrea E Williamson, Richard Lowrie, Donogh Maguire, Steven Ross, James Roy Robertson, Alison Boyle, Clare Duncan, Rebecca Blair, Cian Lombard, Fiona Hughes, Jane Moir, Ailsa Scott, Frank Reilly, Laura Sills, Jennifer Hislop, Stephen Wishart, David Brannan, Rebekah Ramage   +22 more
doaj   +1 more source

Drug Utilisation and Off-Label Use on a German Neonatal Intensive Care Unit: A Retrospective Cohort Study and 10-Year Comparison

Pharmacy, 2020
Pharmacotherapy of neonates is complex and marked to a large extent of off-label use. The implementation of the Paediatric Regulation (2007) gave hope for a change in the safety and efficacy for drugs used in neonatal intensive care units (NICU).
Carmen Geißler, Christopher Schulze, Sebastian Botzenhardt, Wolfgang Rascher, Antje Neubert   +4 more
doaj   +1 more source

Exploring Primary Care Clinicians’ Views about How Best to Implement a Potential Trial around Point-of-Care Tests for Common Infections in South Africa

Diagnostics, 2021
Optimisation of antibiotic prescribing is critical to combat antimicrobial resistance. Point-of-care tests (POCTs) for common infections could be a valuable tool to achieve this in primary care.
Alice Epps, Charlotte Albury, Oliver Van Hecke   +2 more
doaj   +1 more source

To prescribe or not to prescribe? Antibiotics and outpatient infections [PDF]

JAC-Antimicrobial Resistance, 2019
Graphical Abstract.
openaire   +2 more sources