Results 61 to 70 of about 341,268 (305)

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

The competent prescriber: 12 core competencies for safe prescribing [PDF]

, 2013
Prescribing errors remain a significant cause of patient harm. Safe prescribing is not just about writing a prescription, but involves many cognitive and decision-making steps.
Coombes, Ian, Mitchell, Charles, Lum, Elaine   +2 more
core  

Rapid tranquillisation for psychiatric in-patients with a diagnosis of personality disorder: under-recognised issue

BJPsych Open
Background Clinical guidelines for personality disorder emphasise the importance of patients being supported to develop psychological skills to help them manage their symptoms and behaviours.
Carol Paton, Mike J. Crawford, Matthew Hartley, Clive E. Adams, Elena M. Edokpolor Pernia, Olivia Rendora, Thomas R. E. Barnes   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Understanding the medication regimens associated with anticholinergic burden in older people's mental health services in the UK

BJPsych Open
Background Medications with anticholinergic properties are associated with a range of adverse effects that tend to be worse in older people. Aims To investigate medication regimens with high anticholinergic burden, prescribed for older adults under the ...
Thomas R. E. Barnes, Delia Bishara, Alistair Burns, Phyo K. Myint, Olivia Rendora, Elena M. Edokpolor Pernia, Carol Paton   +6 more
doaj   +1 more source

Antipsychotic prescribing practices in real-life (APPREAL study): Findings from the French National Healthcare System Database (2007–2017)

Frontiers in Psychiatry, 2022
BackgroundAntipsychotics are used in a large variety of psychiatric and neurological disorders; investigating their use in real life is important to understand national prescribing practices, as well as to determine the levels of patient adherence ...
Benjamin Rolland, Benjamin Rolland, Faustine Dalon, Noémie Gauthier, Mikaïl Nourredine, Mikaïl Nourredine, Marjorie Bérard, Louise Carton, Georges Brousse, Pierre-Michel Llorca, Flore Jacoud, Eric Van Ganse, Eric Van Ganse, Eric Van Ganse, Manon Belhassen   +14 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Influences on quality of prescribing in breast cancer patients

, 2018
This article presents a discussion on both positive and negative influences on quality of prescribing in clinical practice. It explores how such influences have an impact on breast cancer patients on adjuvant hormonal therapy.
O'Reilly, Helen Anne, Dowling, Maura
core   +1 more source

Managing the misuse potential and risk of psychological harm from gabapentinoids in primary care in New Zealand [PDF]

Journal of Primary Health Care, 2021
Gabapentinoid prescribing is increasing in New Zealand. International evidence suggests that this prescribing trend is followed by increasing harms, including misuse, dependence, overdose, and psychological harms including suicidal thoughts or behaviours.
Ben Hudson, Les Toop, Rose Crossin, Shaun Aindow   +3 more
doaj