Results 91 to 100 of about 1,291,703 (304)

Prescribing trend of antimalarial drugs at the Ghana Police Hospital

Journal of Infection in Developing Countries, 2015
Introduction: Malaria ranks among the top three leading causes of morbidity and mortality in developing countries. Appropriate use of recommended antimalarial drugs is vital in the effective management of malaria.
Daniel Kwame Afriyie, Seth Kwabena Amponsah, Robert Antwi, Stephen Yayra Nyoagbe, Kwasi Agyei Bugyei   +4 more
doaj   +1 more source

Conformal blocks from Wilson lines with loop corrections

, 2018
We compute the conformal blocks of the Virasoro minimal model or its W$_N$ extension with large central charge from Wilson line networks in a Chern-Simons theory including loop corrections.
Hikida, Yasuaki, Uetoko, Takahiro
core   +1 more source

Use of a Molecular Signature Response Classifier to Inform Treatment Selection Improves Clinical Disease Activity Among Patients with Rheumatoid Arthritis Initiating a Biologic or Targeted Synthetic Disease‐Modifying Antirheumatic Drug

Arthritis Care &Research, EarlyView.
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie, Timothy Beukelman, Nicholas P. McCormick, Jeffrey R. Curtis   +3 more
wiley   +1 more source

Cepharanthine alleviates lipopolysaccharide-induced acute lung injury through modulating macrophage polarization

Scientific Reports
Acute lung injury (ALI) is a common, severe respiratory disorder frequently related to acute lung inflammation. As crucial immunoregulatory cells, macrophages critically influence the pathological trajectory of ALI, with their functional states serving ...
Longjiao Dang, Biyao He, Junjie Yang, Jiayu Liu, Yuexia Ding, Wenyu Xin   +5 more
doaj   +1 more source

Immune Checkpoint Inhibitor–Related Myositis and Associated Triad Overlap Syndrome

Arthritis Care &Research, EarlyView.
Objective Immune checkpoint inhibitor (ICI) myositis is a rare but a highly morbid condition, particularly with the ICI myositis triad syndrome of myositis, myocarditis, and myasthenia gravis. We report the clinical characteristics of ICI myositis and all‐cause mortality in these patients.
Selene Rubino, Grant W. Cannon, Brian C. Sauer, Jorge Rojas, Gregory J. Stoddard, Gary A. Kunkel, Jessica A. Walsh, Bryant R. England, Joshua F. Baker, Tawnie J. Braaten   +9 more
wiley   +1 more source

Sishen Pill treats spleen-kidney yang deficiency IBS-D by influencing ATPase activity and intestinal microbiota

Frontiers in Microbiology
BackgroundSishen Pill (SSP) has therapeutic effects on spleen-kidney yang deficiency diarrhea-predominant irritable bowel syndrome (IBS-D). Studies have shown that IBS-D with spleen-kidney yang deficiency is characterized by intestinal microbiota ...
Qi Long, Qi Long, Liwen Li, Liwen Li, Zhoujin Tan, Zhoujin Tan, Na Deng, Na Deng   +7 more
doaj   +1 more source

Effect of Implementing a Dashboard With or Without a Best Practice Alert on HLA‐B*58:01 Testing Rates Among Allopurinol Users at VA Medical Centers

Arthritis Care &Research, EarlyView.
Objective The American College of Rheumatology recommends HLA‐B*58:01 allele testing before the initiation of allopurinol, specifically among Asian and African American/Black patients, due to their increased risk for severe hypersensitivity reactions. However, testing rates remain low at many health care facilities.
Abimbola Fadairo‐Azinge, Gabriela Schmajuk, Sristi Sharma, Colleen P. Flanagan, Sara Faghihi‐Kashani, Ning Zhang, Mary A. Whooley   +6 more
wiley   +1 more source

Syrup Amkesol reduces the level of primary and secondary products of lipid peroxidation and toxic metabolites of nitric oxide in blood serum of immature rats with bronchiolitis

Annals of Mechnikov's Institute, 2019
Aim of this study was to determine the pharmacological effect of syrup Amkesol evaluating the blood serum levels of primary and secondary products of lipid peroxidation, activity of AO enzymes and final rates of NO metabolites in immature rats of ...
K Storozhenko
doaj  

Prospective Study to Assess Long‐Term Outcomes of Chelator‐Based Treatment With Trientine Dihydrochloride in Patients With Wilson Disease

JGH Open
Background and Aims Wilson disease is an inherited disorder of copper metabolism affecting mainly the liver and brain. Trientine dihydrochloride (TETA‐2HCl) is approved for the treatment of Wilson disease in patients (≥ 5 years) intolerant to D ...
Isabelle Mohr, Carlot Kruse, Verena Aliane, Karl Heinz Weiss   +3 more
doaj   +1 more source

Moderators of the Effects of Exercise and Manual Therapy for People With Knee and Hip Osteoarthritis: A Secondary Analysis of a Randomized Clinical Trial

Arthritis Care &Research, EarlyView.
Objective This study aimed to investigate potential moderators influencing the effects of manual therapy and exercise therapy on pain and functional outcomes in individuals with knee and/or hip osteoarthritis, using data from the MOA trial. This is a secondary analysis of data from the MOA trial that compares the clinical effectiveness of manual ...
Daniel Cury Ribeiro, Sarah E. Lamb, J. Haxby Abbott   +2 more
wiley   +1 more source