Results 151 to 160 of about 79,890 (335)

Phase IIb Trial for the Palliative Treatment of Patients With Primary Hepatic Malignancy Unable to Receive Curative Treatment: Efficacy of Colchicine

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This trial was to evaluate the efficacy and the safety of colchicine for the palliative treatment of patients with primary hepatic malignancy unable to receive curative treatment. Forty hepatocellular carcinoma (HCC) patients and two intrahepatic cholangiocarcinoma (ICC) patients signed the informed consents.
Zu‐Yau Lin   +8 more
wiley   +1 more source

US Food and Drug Administration's Risk Evaluation and Mitigation Strategy for Extended-Release and Long-Acting Opioids Pros and Cons, and a European Perspective [PDF]

open access: yes, 2012
Prescriptions for opioid analgesics to manage moderate-to-severe chronic non-cancer pain have increased markedly over the last decade. An unintentional consequence of greater prescription opioid utilization has been the parallel increase in misuse, abuse
Craig, D   +2 more
core  

Bipolar Disorder as a Long‐Term Risk Factor for Parkinson's Disease: A Nationwide Case–Control Study

open access: yesMovement Disorders, EarlyView.
Abstract Background Previous studies suggest an association between bipolar disorder (BD) and an increased risk of Parkinson's disease (PD), but the long‐term temporal relationship remains unclear. Particularly, it is unclear whether the risk of PD is influenced by the duration since BD diagnosis.
Elina Jaakkola   +5 more
wiley   +1 more source

The Misuse of Over-the-Counter NSAIDs [PDF]

open access: yes, 2019
Over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs) are some of the most frequently used analgesics. The misuse of these medications occurs frequently and often without the patient’s realization.
Hudson, Sara
core   +1 more source

Healthcare Resource Use and Cost: The Impact of Adopting an Abuse-Deterrent Formulation of Extended Release Morphine

open access: yesClinicoEconomics and Outcomes Research, 2020
Louis F Rossiter, 1 Winghan Jacqueline Kwong, 2 Elizabeth Marrett 2 1The College of William and Mary, Williamsburg, VA 23187, USA; 2US Medical Affairs, Daiichi Sankyo, Inc., Basking Ridge, NJ 07920, USACorrespondence: Elizabeth MarrettUS Medical ...
Rossiter LF, Kwong WJ, Marrett E
doaj  

Prevalence and Correlates of Prescription Drug Misuse in a Nationwide Population Survey in Taiwan. [PDF]

open access: yesInt J Environ Res Public Health, 2021
Liu SW   +5 more
europepmc   +1 more source

Underlying Mechanisms of the Treatment Efficacy of (R, S)‐Ketamine for Post‐Traumatic Stress Disorder and Depression: A Review

open access: yesMedicine Advances, EarlyView.
Research shows that (R, S)‐ketamine and its stereoisomers effectively reduce symptoms of post‐traumatic stress disorder (PTSD) and treatment‐resistant depression, with (R)‐ketamine offering similar benefits with fewer side effects. Evidence highlights specific neural circuits and regions, including the dentate gyrus, prefrontal cortex, vCA3, dorsal ...
Thomas Edward Cutting   +1 more
wiley   +1 more source

Development and Acceptability of a Method to Investigate Prescription Drug Misuse in Daily Life: Ecological Momentary Assessment Study (Preprint)

open access: gold, 2020
Lauren M. Papp   +6 more
openalex   +1 more source

Confronting the opioid crisis: Practical pain management and strategies: AOA 2018 critical issues symposium [PDF]

open access: yes, 2019
The United States is in the midst of an opioid crisis. Clinicians have been part of the problem because of overprescribing of narcotics for perioperative pain management.
Hsu, Joseph R   +4 more
core   +1 more source

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