Results 161 to 170 of about 235,228 (303)

Stress History Establishes a Transient Tolerant State That Shapes Antibiotic Survival Upon Resuscitation

Advanced Science, EarlyView.
High‐throughput single‐cell analysis of resuscitating bacteria reveals a starvation‐history‐dependent transiently tolerant subpopulation that survives β$\beta$‐lactam exposure by temporarily reducing growth. Distinct from classical persisters, these actively growing yet dynamically modulated cells dominate survival across clinically relevant antibiotic
Kieran Abbott, Georgeos Hardo, Ruizhe Li, Jack Bradley, Ashraf Zarkan, Somenath Bakshi   +5 more
wiley   +1 more source

The Benefits and Costs of Newer Drugs: Evidence from the 1996 Medical Expenditure Panel Survey [PDF]

The nation's spending for prescription drugs has grown dramatically in recent years. Previous studies have shown that the replacement of older drugs by newer, more expensive, drugs is the single most important reason for this increase, but they did not ...
Frank R. Lichtenberg
core  

Developmentally Inspired Bioprinting of Nascent Multicellular Human Heart Tissue Through in Situ Differentiation and Morphogenesis of iPSCs

Advanced Science, EarlyView.
A developmentally inspired bioprinting approach enables the fabrication of pluripotent tissues that undergo shape‐morphing and in situ cardiac lineage specification. This method employs embedded bioprinting to deposit iPSCs within soft granular hydrogels to create pluripotent tissue constructs that undergo cell‐mediated shape morphogenesis.
Ankita Pramanick, Juhi Chakraborty, Orlaith Kennedy, Hey Wei Wong, Sogol Kianersi, Daniel Kelly, Vasileios Sergis, Abhay Pandit, Andrew C. Daly   +8 more
wiley   +1 more source

Prescription Drug Pricing [PDF]

Annals of Emergency Medicine, 2018
openaire   +2 more sources

Clinical Characteristics of Patients With Overdose Engaging in Nonmedical Use of Prescription Drugs: A Single-Center Study in Japan. [PDF]

Acute Med Surg
Shioya N, Inoue N, Nishitani T, Kawashima N, Tsukamoto Y, Sato T, Sadamoto Y, Naito Y, Hazama K, Shichinohe Y.   +9 more
europepmc   +1 more source

"Napsterizing" Pharmaceuticals: Access, Innovation, and Consumer Welfare [PDF]

We analyze the effects on consumers of an extreme policy experiment -- Napsterizing' pharmaceuticals -- whereby all patent rights on branded prescription drugs are eliminated for both existing and future prescription drugs without compensation to the ...
James W. Hughes, Edward A. Snyder, Michael J. Moore   +2 more
core  

Cyclic Mechanical Loading of Cardiomyocytes via Pressure‐Driven Non‐Planar Membrane Deformation in a Bioreactor System

Advanced Science, EarlyView.
In this research article, Mansoor and coworkers present a novel device that applies controlled mechanical stimuli to cardiomyocytes using pressure‐driven membrane deformation. By exposing cells to physiologically and pathologically relevant loading conditions, the platform reproduces distinct structural, functional and molecular responses associated ...
Haris Mansoor, Gabrielle Juul, Jil Patel, Heran Pradhan, Gram Hepner, Jackson Jewell, Mark Bardin, Ryan Slusser, Abigail Glezer, Leda Klouda, Melikhan Tanyeri, Anita Saraf   +11 more
wiley   +1 more source

Direct-to-Consumer Advertising of Prescription Drugs: What Can the Swiss Experience Tell Policy-Makers in the United States? [PDF]

Cureus
Umaru OT, Aremu TO.
europepmc   +1 more source

Photonic‐Enabled Energy‐Efficient Transparent Neuromorphic Computing Devices: A Review

Advanced Science, EarlyView.
Transparent photonic neuromorphic computing devices merge optics and brain‐inspired computing to overcome von Neumann bottlenecks with ultrafast, low‐energy processing. By exploiting transparent oxides, 2D materials, phase‐change materials, and hybrid heterostructures, these platforms enable photonic synapses, memory, and logic for see‐through edge ...
Shuvaraj Ghosh, Ki‐bum Lee, Junghyeon Lee, Seunghee Cho, Malkeshkumar Patel, Hangfei Li, Yu Wen, Ye Zhou, Joondong Kim   +8 more
wiley   +1 more source

Prescription Drugs in Pregnancy and Congenital Malformations: A Population-Based Safety Screening Study. [PDF]

Pharmacoepidemiol Drug Saf
Broe A, Pottegård A, Munk-Olsen T, Hallas J, Bliddal M, Petersen I, Damkier P.   +6 more
europepmc   +1 more source