Results 201 to 210 of about 1,396,233 (302)

CRISPR and Gene Augmentation Rescue Trabecular Meshwork Dysfunction in iPSC Models of Lowe Syndrome

open access: yesAdvanced Science, EarlyView.
By modeling Lowe syndrome using patient‐derived iPSCs, this study establishes a human disease model that faithfully recapitulates OCRL deficiency‐associated ciliary and cytoskeletal defects. The model enables evaluation of both mutation‐agnostic DNA augmentation and CRISPR‐mediated mutation correction strategies, both of which restore OCRL function and
Siyu Chen   +11 more
wiley   +1 more source

Self‐Sustaining Sensing Systems: Integration Strategies and Signal–Power Matching in Energy‐Harvesting Electronics

open access: yesAdvanced Science, EarlyView.
Energy‐harvesting‐integrated sensors couple ambient energy conversion with sensing, processing, and wireless communication. This review organizes recent progress through integration architectures and operating principles, revisiting co‐packaged, monolithic, and co‐functional designs together with always‐on, event‐driven, and multi‐modal sensing modes ...
Taehyun Park   +5 more
wiley   +1 more source

SOC Mismatch–Driven Inter‐Particle Synchronization via Internal Li‐Ion Transfer: An Unrecognized Electrode‐Emergent Degradation Pathway in Ni‐Rich Composite Cathodes

open access: yesAdvanced Energy Materials, EarlyView.
Composite cathode degradation is not merely the sum of its particles. Kinetically mismatched populations develop state‐of‐charge differences that drive spontaneous internal Li‐ion transfer; the accompanying transient currents accelerate surface degradation.
Seheon Oh   +5 more
wiley   +1 more source

Valorizing Food Waste (Banana Peel) Into an Edible Product: A Study on the Effect of Banana Peel Flour on the Physicochemical, Antioxidant, Textural, and Sensory Properties of Cookies

open access: yesAgriFood: Journal of Agricultural Products for Food, EarlyView.
This study investigated the impact of banana peel flour (BPF) incorporation on cookies' nutritional, functional, physical, and antioxidant properties. The inclusion of BPF led to significant changes in the moisture, protein, crude fat, and ash contents of the developed cookies.
Km. Gudiya   +3 more
wiley   +1 more source

Impact of Histopathological Response on Outcomes After Surgical Resection Following Carbon‐Ion Radiotherapy for Pancreatic Cancer With Arterial Involvement

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim Carbon‐ion radiotherapy (CIRT) provides superior dose distribution and higher biological effectiveness than conventional X‐ray radiotherapy and has emerged as a promising component of multidisciplinary treatment for advanced pancreatic ductal adenocarcinoma (PDAC).
Kenichiro Araki   +9 more
wiley   +1 more source

Toward Knowledge‐Guided AI for Inverse Design in Manufacturing: A Perspective on Domain, Physics, and Human–AI Synergy

open access: yesAdvanced Intelligent Discovery, EarlyView.
This perspective highlights how knowledge‐guided artificial intelligence can address key challenges in manufacturing inverse design, including high‐dimensional search spaces, limited data, and process constraints. It focused on three complementary pillars—expert‐guided problem definition, physics‐informed machine learning, and large language model ...
Hugon Lee   +3 more
wiley   +1 more source

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