This study exploits the plasticity of ASCs‐derived cartilage organoids which generate a perichondrial layer of MSCs when exposed to cyclic chondrogenic/proliferative cues. Using these organoids as building blocks, we develop (i) Phalange Shaped Tissue Engineered Cartilage (Pa‐TECs), recapitulating endochondral ossification suitable for the treatment of
Pablo Pfister +14 more
wiley +1 more source
Changes in Type 2 Diabetes Medications Among Primary Care Patients After California's 2022 Medicaid Expansion. [PDF]
Ro AE +5 more
europepmc +1 more source
A Soft Microrobot for Single‐Cell Transport, Spheroid Assembly, and Dual‐Mode Drug Screening
A soft, untethered hydrogel microrobot enables precise single‐cell delivery, self‐assembly into 3D spheroids, and real‐time thermal actuation. Driven by light‐induced convection and embedded with gold nanorods and temperature sensors, the microrobot guides cells, modulates local microenvironments, and supports drug testing.
Philipp Harder +3 more
wiley +1 more source
Evaluating time to access opioid treatment for patients with insurance that requires the Safe & Effective Management of Pain prior authorization form vs others. [PDF]
Riffe LP, Carico R, Dunaway S.
europepmc +1 more source
Remorphable Architectures: Reprogramming Global Bistability through Locally Bistable Metamaterials
Local bistable reconfiguration in mechanical metamaterials is leveraged in globally bistable architectures to enable in situ reprogrammable transition pathways through state flip of individual building blocks. The local‐to‐global correspondence of instabilities empowers soft robotic systems with on‐demand morphing traits, as well as aerospace ...
Lei Wu +3 more
wiley +1 more source
Implementation of a Best Practice Advisory to alert inpatient providers of necessary discharge prescriptions for insulin and supplies for patients with diabetes. [PDF]
Lundholm MD +3 more
europepmc +1 more source
Multidisciplinary medication review during older patient hospitalization according to STOPP/START criteria reduces potentially inappropriate prescriptions: MoPIM cohort study [PDF]
S Ortonobes Roig +27 more
openalex +1 more source
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Metal‐free carbon catalysts enable the sustainable synthesis of hydrogen peroxide via two‐electron oxygen reduction; however, active site complexity continues to hinder reliable interpretation. This review critiques correlation‐based approaches and highlights the importance of orthogonal experimental designs, standardized catalyst passports ...
Dayu Zhu +3 more
wiley +1 more source

