Results 21 to 30 of about 200,641 (267)

Postbiotic from Lactobacillus acidophilus Inhibits Ferroptosis in Intestinal Stem Cells via Microbiota–AhR Axis to Mitigate Colitis

Food Frontiers
Inflammatory bowel disease (IBD) is a chronic, progressive intestinal disorder. Dysbiosis of the gut microbiota is strongly implicated in the onset and progression of IBD. Microbiome‐based interventions offer promising therapeutic potential. Lacidophilin
Denglong Sun, Chenxuan Wang, Qigui Fan, Yang Zhan, Xiaoying Cheng, Jingwen Zhang, Qinxin Wang, Yingmeng Li, Qiong Li, Yanxia Xiong, Wenjun Liu   +10 more
doaj   +1 more source

Overview of Research on Essential Oils of Zanthoxylum bungeanum: Composition, Activity, Applications, and Challenges

Pharmaceuticals
As the main active component of Zanthoxylum bungeanum, its volatile oil (ZEO) exhibits diverse pharmacological activities, including insecticidal, antibacterial, anti-inflammatory, and anti-tumor effects.
Qing Du, Yuwan Diao, Yu Meng, Zihan Wang, Jing Zhang, Tingting Wu, Qiaoyi Huang, Xiaoying Huang, Ming Yang   +8 more
doaj   +1 more source

Analyser la place des prescriptions dans l’activité d’un enseignant débutant d’éducation physique et sportive en croisant les regards didactique et ergonomique

eJournal de la Recherche sur l'Intervention en Éducation Physique et Sport, 2018
Our study focuses on the use of official prescriptions on the conduct of the activity of a beginning teacher in physical education (PE). By combining didactic and ergonomic approaches, we question both elements related to the teacher's gestures and the ...
Fabienne Brière-Guenoun, Teddy Mayeko
doaj   +1 more source

Prescription analysis of rheumatology and endocrinology departments of a teaching hospital in Western India

Journal of Current Research in Scientific Medicine, 2022
Background: Prescription analysis is the simplest method to observe the current treatment practice in any health-care setting. Biopharmaceuticals are a class of drugs that hold great promise in treating diseases.
Vikas Yadav, Sanjay Jaiswal, Sharan Shyam   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Le prêt des collections au regard de la conservation préventive : prescriptions et suivi

In Situ, 2012
The author presents how preventive conservation should be involved in loan policy in order to maximize conservation. She focuses on artwork condition assessment as well as slow and cumulative degradations, and more particularly for paintings.
Claire Bergeaud
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Technological advances and challenges in constructing complex gut organoid systems

Frontiers in Cell and Developmental Biology
Recent advancements in organoid technology have heralded a transformative era in biomedical research, characterized by the emergence of gut organoids that replicate the structural and functional complexity of the human intestines. These stem cell-derived
Longjin Zheng, Longjin Zheng, Yang Zhan, Yang Zhan, Chenxuan Wang, Chenxuan Wang, Qigui Fan, Qigui Fan, Denglong Sun, Denglong Sun, Yingmeng Li, Yingmeng Li, Yanxia Xiong, Yanxia Xiong   +13 more
doaj   +1 more source

Development and implementation of a workshop for young adults with diabetes entering college and the workforce

Frontiers in Endocrinology, 2023
The process of transitioning from pediatric to adult diabetes care for adolescents and young adults is challenging. This transition period may include many life changes, and can be fraught with worsening glycemic control leading to increased risk for ...
Margaret West, Aniket Sidhaye, Meredith Thivierge, Risa M. Wolf   +3 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source