Results 61 to 70 of about 304,260 (311)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Reunderstanding the classical prescription Banxia Xiexin Decoction: new perspectives from a comprehensive review of clinical research and pharmacological studies

open access: yesChinese Medicine
Classical prescriptions of Chinese medicine represent the crystallized wisdom of millennia of clinical practice, enduring as cornerstones of therapeutic intervention due to their demonstrated efficacy across generations.
Chang Liu   +7 more
doaj   +1 more source

Effect of freeze-pressure regulated extraction technology on the physicochemical properties and pharmacological activities of guizhi extract

open access: yesFrontiers in Chemistry
Extraction is the core process for obtaining bioactive compounds from medicinal plants. Enhancing the extraction efficiency of aromatic herbs has become a critical challenge.
Huiling Zhang   +9 more
doaj   +1 more source

A Prescription for Song [PDF]

open access: yesJournal of General Internal Medicine, 2011
“iBuenos dias a todas! ?Como estan mis queridas mujeres hermosas?”1 I sing as I glide into the hospital room, anticipating slightly less enthusiasm from my audience. Surely enough, the onslaught begins. With my question, I open the floodgates, and begin to field complaints and requests and questions from four patients simultaneously. It is the start
openaire   +2 more sources

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

PRESCRIPTION “SUBSTITUTION.” [PDF]

open access: yesSouthern Medical Journal, 1916
n ...
openaire   +1 more source

Calibrating Star Formation Rate Prescriptions at Different Scales (10 pc-1 kpc) in M31

open access: yes, 2019
We calibrate commonly used star formation rate (SFR) prescriptions using observations in five kiloparsec-sized fields in the nearby galaxy Andromeda (M31) at 10 pc spatial resolution.
Tomičić, Neven   +11 more
core   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

Trends and Patterns of Antibiotic Prescriptions in Primary Care Institutions in Southwest China, 2017–2022

open access: yes, 2023
Changlan Li,1,* Zhezhe Cui,2 Du Wei,3,4,* Quan Zhang,5,* Junli Yang,3 Wenju Wang,1 Xiaobo Luo,1 Yue Chang3,4 1School of Public Health, the key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education ...
Yang J   +7 more
core  

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