Results 101 to 110 of about 9,155,097 (318)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Influence of Vertical Navigation Metaphors on Presence

, 2014
A sense of spatial presence as a feeling of "being there" is an important part of the virtual experience. Navigation is a fundamental task in virtual environments and the specific navigation methods that are employed influence a user´s sense of
Kaufmann, Hannes, Vasylevska, Khrystyna
core  

Presence-absence matrices

, 2016
Six presence-absence matrices generated to detect non-random species co-occurrence patterns using EcoSim (Gotelli & Entsminger 2004). Rows correspond to the species sampled in this study.
Geoff Lowe (3282807), Pante, Eric, Therriault, Thomas W., Lowe, Geoff, Scott R. Gilmore (3282813), Castelin, Magalie, Cathryn L. Abbott (3282810), Abbott, Cathryn L., Rick Harbo (3282819), Niels Van Steenkiste (394076), Eric Pante (110501), Magalie Castelin (468505), Van Steenkiste, Niels, Thomas W. Therriault (3282816), Harbo, Rick, Gilmore, Scott R.   +15 more
core   +1 more source

Using Behavioral Realism to Estimate Presence: A Study of the Utility of Postural Responses to Motion Stimuli [PDF]

, 2000
We recently reported that direct subjective ratings of the sense of presence are potentially unstable and can be biased by previous judgments of the same stimuli (Freeman et al., 1999).
Meddis, R, Avons, Steve, Ijsselsteijn, Wijnand, Meddis, R., Pearson, Don E., Freeman, J Jonathan, Jonathan Freeman, Freeman, J., Don E. Pearson, Freeman, Jonathan, Pearson, DE Don, Wijnand IJsselsteijn, Meddis, Ray, S. E. Avons, Avons, S.E., Ray Meddis, IJsselsteijn, WA Wijnand, Avons, SE, Pearson, D.E., IJsselsteijn, W.A., IJsselsteijn, W.A.; id_orcid   +20 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Spaces of the possible: developing the Radical Film Network in Scotland

, 2020
This chapter reflects on some key events in the development of the Radical Film Network (RFN) in Scotland between 2015 and 2019. It draws on active participation in the research activity, interviews with key individuals, and autoethnography – a ...
David Archibald, Archibald, David
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source