Results 171 to 180 of about 16,483,786 (303)

Anticoagulation Reversal and Treatment Strategies in Major Bleeding: Update 2016

Western Journal of Emergency Medicine, 2016
Steve Christos, Robin Naples
doaj   +1 more source

The Triad of Dying: A framework for palliation and compassionate decision-making in the ICU. [PDF]

J Intensive Care Soc
Gilbert-Kawai N, Presswood E.
europepmc   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Everyday presences

Cultural Studies, 2004
Andrew Metcalfe, Ann Game
openaire   +1 more source

Correction for Anand et al., Convolutional neural networks outperform other presence-only species distribution modeling algorithms. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

Microprolactinoma (Pituitary Adenoma) as a Cause of Secondary Headache in a Pediatric Patient With Pain and Restricted Mouth Opening: A Case Report. [PDF]

Case Rep Dent
Draghici R, Saracutu OI, Pollis M, Manfredini D.   +3 more
europepmc   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Newsroom: RWU Law Expands Providence Presence [PDF]

, 2015
Roger Williams University School of Law
core   +1 more source

Not simply two sides of the same coin: Target enhancement and distractor suppression draw on independent neural mechanisms. [PDF]

Atten Percept Psychophys
Khodayari N, Egeth H, Courtney SM.
europepmc   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source