Results 121 to 130 of about 190,228,706 (268)

Dual Impacts On Meaning In Life In Older Persons Volunteering For Elderly Mental health Program

open access: yes, 2019
Volunteering provides sense of meaning in life. The impact of volunteering on different dimensions of meaning in life and the mechanisms explaining the effects have been rarely researched.
Sze, CY   +7 more
core   +1 more source

The relationship between problematic mobile phone use and meaning in life among adolescents: a latent profile analyses

open access: yesBMC Psychology
Purpose This study utilized Latent Profile Analysis to identify distinct profiles of meaning in life (MiL) among adolescents. Additionally, it aimed to investigate the relationships and specific impacts of sociodemographic variables and problematic ...
Naiyang Peng   +4 more
doaj   +1 more source

Ability to mentalize and the sense of meaning in life in the professional group of nurses: a cross-sectional study

open access: yesMedycyna Pracy
Background Mentalization supports emotion regulation and interpersonal functioning, and meaning in life is a key psychological resource in nursing. This study examined associations between mentalizing capacity and meaning in life among practicing nurses.
Łukasz Krzewiński, Patrycja Basińska
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

The relation of search for and presence of meaning in life to attitudes about death [PDF]

open access: yes, 2010
Various theories have hypothesized and research has corroborated that individuals who find meaning in life are more accepting of their own mortality. More recently, scholars have noted important distinctions between individuals who report presence of ...
Powell, Kevin
core   +1 more source

The mediating role of meaning in life between experiential avoidance and death anxiety among cancer patients: a cross-sectional study

open access: yesBMC Cancer
Background Death anxiety is thought to cause a range of mental disorders among cancer patients, which may affect their mental health and even quality of life.
Yixia Yan   +9 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Meaning in Life, Substance Use Severity, and Depressive Symptoms in Adolescents with Substance Use Disorder

open access: yesUludağ Üniversitesi Tıp Fakültesi Dergisi
This study aimed to examine the relationships among meaning in life, depressive symptoms, and substance use severity in adolescents diagnosed with substance use disorder (SUD). This cross-sectional study included 75 adolescents aged 15–18 years diagnosed
Hande Şirin   +3 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

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