Results 111 to 120 of about 27,158,111 (340)

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

Deals and Dealings: Inconclusive Peace and Treacherous Trade along the South Sudan–Uganda Border Geschäfte und Deals: Gefährdeter Frieden und riskante Handelsbeziehungen entlang der südsudanesisch-ugandischen Grenze

open access: yesAfrica Spectrum, 2012
Since Sudan’s Comprehensive Peace Agreement (CPA) was signed, its border with Uganda has become a hub of activity. Contrasting developments on the Ugandan side of the border with those on the South Sudanese side, the paper draws on empirical fieldwork to
Mareike Schomerus, Kristof Titeca
doaj  

On Agnotology as Built-in Ignorance Über Agnotologie als produziertes Unwissen

open access: yesAfrica Spectrum, 2013
Contribution to the Debate on Anthropology in Africa in Africa Spectrum.Beitrag zur "Debate on Anthropology in Africa" in Africa Spectrum.
Jean-Pierre Warnier
doaj  

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Political Representation of Minorities as Collateral Damage or Gain: The Batwa in Burundi and Rwanda

open access: yesAfrica Spectrum, 2014
There is a remarkable discrepancy between the political representation of the Batwa ethnic minority group in Burundi compared to in Rwanda. Whereas Rwanda’s focus on citizenship prevents the Batwa from claiming recognition as a politically salient ...
Stef Vandeginste
doaj  

The Force of Action: Legitimizing the Coup in Bamako, Mali Die Kraft zum Handeln: Die Legitimierung des Staatsstreichs in Bamako, Mali

open access: yesAfrica Spectrum, 2012
The coup d’état that occurred in Bamako in March 2012 brought a previously unknown army captain named Amadou Sanogo to power. This paper analyses Malian media reports to explore how Sanogo and his associates sought to legitimize their takeover with ...
Bruce Whitehouse
doaj  

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