Results 131 to 140 of about 19,830,962 (273)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Death or Dearth of Democracy in Zimbabwe?
Africa Spectrum, 2014 Constribution to the Debate on the Political Culture in (Southern) African States in Africa Spectrum.
David Moore
doaj
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Review: Sanya Osha (ed.), The Social Contract in Africa (2014)
Africa Spectrum, 2014 Review of the edited volume:Sanya Osha (ed.), The Social Contract in Africa, Pretoria: Africa Institute for South Africa, 2014, ISBN 978-0-7983-0444-3, 200 ...
Damian Chukwudi Ukwandu
doaj
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Too Soon to Tell? Land Reform in Zimbabwe Too Soon to Tell? Die Landreform in Zimbabwe
Africa Spectrum, 2011 Review Article: Ian Scoones, Nelson Marongwe, Blasio Mavedzenge, Jacob Mahenehene, Felix Murimbarimba and Crispen Sukume (2010), Zimbabwe’s Land Reform: Myths and Realities, London: James Currey, ISBN 978-1-84701-024-7; Harare: Weaver Press, ISBN 978-1 ...
Roger Southall
doaj
Fuzzy interval net present value [PDF]
In this paper we conjugate the operative usability of the net present value with the capability of the fuzzy and the interval approaches to manage uncertainty. Our fuzzy interval net present value can be interpreted, besides the usual present value of an
Silvio Giove, Marco Corazza
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Metacognitive Prediction of Creative Performance in Divergent Thinking. [PDF]
Psych JSun T +5 more
europepmc +1 more source