Results 201 to 210 of about 8,901,738 (246)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Comment on suspicious for malignancy cytology: nuclear characteristics deserve special attention in reported cytology analysis - real-world scenario cohort in thyroidology. [PDF]

Arch Endocrinol Metab
Sengul I, Sengul D.
europepmc   +1 more source

Poster Presentation

Experimental Animals, 2018
openaire   +3 more sources

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Insight into molecular phylogeny and haplotype diversity of the dog louse fly (Hippobosca longipennis) in India. [PDF]

BMC Vet Res
Dhankhar V, Nehra AK, Moudgil AD.
europepmc   +1 more source

Hipo 5 Presentes futuribles, futuros presentables/Futurable Presents, Presentable Futures

, 2017
García Triviño, Francisco Antonio, Psegiannaki, Katerina, Nieto Fernandez, Fernando   +3 more
openaire   +1 more source

Characteristics of chromosomal instability‑related lncRNAs associated with progression and prognosis in breast cancer. [PDF]

Mol Med Rep
Chen Q, Chen H, Yang H, Tao Y, Zhu X.
europepmc   +1 more source