Results 31 to 40 of about 25,689,350 (343)
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Wooster Magazine: Fall 2016 [PDF]
, 2016 The fall 2016 issue of the Wooster magazine features a section dedicated to Sarah Bolton, the College of Wooster’s 12th President, the renovations to the Cornerstone Playlab, and voices from the past, a creative endeavor with portraits by Mattie Cannon ...
Crosbie, Karol
core +1 more source
Wooster Magazine: Spring 2021 [PDF]
, 2021 The spring issue of Wooster magazine showcases The College of Wooster’s new Pathways Programs which bring together interdisciplinary courses, experiential learning, and ongoing reflection for current students. Alumni working in the areas of Public Health,
Stanowick, Caitlin Paynich
core +1 more source
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
McTaggart’s paradox and its consequences [PDF]
Filozofija i Društvo, 2015 McTaggart’s explanation of the human understanding of time, which uses the time series, is a significant moment in the history of philosophy, and his attempt to prove time’s unreality had strong but diverse reactions.
Đorđević Strahinja
doaj +1 more source
Wooster Magazine: Summer 2014 [PDF]
, 2014 This Summer 2014 edition of the Wooster Magazine begins with an article regarding liberal arts education and Moot Court. The Shack has officially been knocked down and an image from that is featured on page four.
Crosbie, Karol
core +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Diphthamide synthesis is linked to the eEF2‐client chaperone machinery
FEBS Letters, EarlyView.The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr +4 more
wiley +1 more source
Revista de Estudios Brasileños, 2016 Texto de presentación del número 5 (volumen 3) de la Revista de Estudios Brasileños.
José Manuel SANTOS PÉREZ +1 more
openaire +8 more sources
Characterization of fungal carbonyl sulfide hydrolase belonging to clade D β‐carbonic anhydrase
FEBS Letters, EarlyView.Here, we performed a functional analysis of the fungal enzymes belonging to clade D of the β‐class carbonic anhydrase family (β‐D‐CA). The β‐D‐CAs in the basidiomycete Gloeophyllum trabeum and the ascomycete Trichoderma harzianum showed very low activity in the hydration of CO2 but exhibited high activity in the hydrolysis of carbonyl sulfide (COS ...
Ryuka Iizuka +6 more
wiley +1 more source