Results 151 to 160 of about 3,967,273 (291)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Early surgical outcomes of cardiac myxoma resection according to dominant clinical phenotype in adult patients. [PDF]

North Clin Istanb
Karakaya HC, Ceylan L, Yilmaz R, Yargi M, Ketenci B.   +4 more
europepmc   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Souvenir of the silver jubilee of the Sacred Heart Presentation Convent, San Francisco, California, 1869-1894

, 1894
Sacred Heart Presentation Convent (San Francisco, Calif.)
core  

Community Webs: Building Inclusive Web & Digital Archives through Community-Oriented Programs [Jefferson Bailey Presentation]

Presentation for the IIPC General Assembly and Web Archiving Conference held on April 24-26, 2024 held at the National Library of France in Paris. This presentation details the Community Webs program whose mission is to advance the capacity for public ...
Bailey, Jefferson
core  

IL-15 trans-presentation at the innate-adaptive interface: mechanisms and translation in cancer immunotherapy. [PDF]

Oncoimmunology
Goldman CK.
europepmc   +1 more source

Presentación

América Latina Hoy, 2018
Ilka TREMINIO SÁNCHEZ, Cecilia Graciela RODRÍGUEZ   +1 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Effects of Presentation Form and Presentation Timing in AR-HUD Takeover Displays on Driver Visual Attention: An Eye-Tracking Study. [PDF]

J Eye Mov Res
Chen K, Li J, Chen M.
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source