Early Rule Out of Myocardial Infarction With a Novel High-Sensitivity Cardiac Troponin T Assay.
Thurston AJF +25 more
europepmc +1 more source
Factors associated with delayed hospital presentation following stroke in Senegal: a mixed methods study. [PDF]
Njohjam MN, Ngoule MO, Niakam FT.
europepmc +1 more source
Rhode Island Department of Corrections: Presentation [PDF]
Barron, Danielle, O\u27Connor, Caitlin
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Determinants of tuberculosis presentation and successful treatment outcome among tuberculosis patients in Geita, Tanzania. [PDF]
Nlula JA +5 more
europepmc +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Which healthcare services did children and adolescents use before presentation at specialised outpatient clinics for post-COVID-19 condition? Descriptive findings from the Post-COVID Kids Bavaria study. [PDF]
Koenig M +11 more
europepmc +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Does Respiratory Rate Increase Before Respiratory Exacerbations in Pediatric Neuromuscular Patients Requiring Ventilation? [PDF]
Ghirardo S +3 more
europepmc +1 more source

