Results 171 to 180 of about 3,967,273 (291)

Entrepreneurship and Innovation: from isolated dreamer to clusters.

, 2008
TESTA, STEFANIA, DEAK C. INVITED PRESENTATION AT   +1 more
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Melanoma in people living with HIV: antigen-presentation loss, spatial immune escape, and inclusive immunotherapy trials. [PDF]

Front Immunol
Giubellino A, Mansini AP.
europepmc   +1 more source

Presentación

Cuadernos Dieciochistas, 2014
Luis BAGUÉ QUÍLEZ, Antonio de MURCIA CONESA   +1 more
doaj  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Immune evasion driven by lipid metabolic reprogramming in endocrine-resistant HR⁺ breast cancer: antigen presentation defects and T-cell dysfunction. [PDF]

Front Immunol
Gong L, Zhao Y, Che M, Zhang X, Zhang D, Lu W.   +5 more
europepmc   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Oral Presentations and Poster Presentations

British Journal of General Practice, 2020
openaire   +3 more sources

Outcomes of a state-wide virtual emergency department in Victoria, Australia: a linked data analysis of emergency department utilisation and hospital use. [PDF]

Lancet Reg Health West Pac
Sher LM, Jessup RL, Boyd JH, Hutton J, Suleiman M, Lawrence J, Miller S, Nehme Z, Bevan D, Semciw AI.   +9 more
europepmc   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source