Results 111 to 120 of about 141,446 (365)

Revolutionizing Impact of Point of Care Ultrasound (Pocus): A Game-Changer for Decision Making at Bedside Especially in Emergency Obstetrics and Gynecology

open access: yesJournal of Gandhara Medical and Dental Sciences
Dear Editor, I am writing to highlight the transformative potential of Point-of-Care Ultrasound (POCUS) in emergency obstetrics and gynecology. It provides immediate bedside imaging, enabling life-saving decisions without delays. Its portability, cost-
Sadia Shoukat
doaj  

Comprehensive Profiling of N6‐methyladnosine (m6A) Readouts Reveals Novel m6A Readers That Regulate Human Embryonic Stem Cell Differentiation

open access: yesAdvanced Science, EarlyView.
This research deciphers the m6A transcriptome by profiling its sites and functional readout effects: from mRNA stability, translation to alternative splicing, across five different cell types. Machine learning model identifies novel m6A‐binding proteins DDX6 and FXR2 and novel m6A reader proteins FUBP3 and L1TD1.
Zhou Huang   +11 more
wiley   +1 more source

HRS Degradation‐Induced Nicotinamide Deficiency in Placental Extracellular Vesicles Triggers Preeclampsia by Disrupting Maternal‐Fetal Immune Homeostasis

open access: yesAdvanced Science, EarlyView.
This study shows that lower NAM levels in PE‐derived pEVs correlate with disease severity. NAM‐deficient pEVs reduce Th1 and Th17 inhibition, leading to PE‐like symptoms. NAM in pEVs inhibits Th1 via SIRT1 and Th17 via macrophages. Reduced NAM in PE‐EVs is due to decreased HRS expression in trophoblasts, resulting from elevated HSP27.
Haiyi Fei   +10 more
wiley   +1 more source

Ultrasound-Guided Urokinase in the Remedy of Spontaneous Vaginal Hematoma After Vaginal Delivery: A Case Report

open access: yesInternational Journal of Women's Health, 2023
Jin Shang,1 Juan Li,2 Qing Bai,2 Yongmei Wang,2 Hongjian Chen,1 Shunxu Li2 1Department of Ultrasound, The Third People’s Hospital of Yunnan, Kunming, People’s Republic of China; 2Department of Obstetrics, The Third People’s Hospital of Yunnan, Kunming ...
Shang J   +5 more
doaj  

Efferocytosis‐Driven Polyamine Metabolism in Macrophages Enhances Cancer Stem Cell Enrichment after Chemotherapy in Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
Chemotherapy‐induced efferocytosis drives ovarian cancer stem cell enrichment. By engulfing apoptotic cancer cells, macrophages upregulate ODC1 and produce putrescine, which elevates osteopontin (OPN) expression. Secreted OPN then activates the CD44 receptor on cancer cells, promoting stemness and chemoresistance.
Wenhan Li   +19 more
wiley   +1 more source

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