Results 31 to 40 of about 141,446 (365)

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Analysis of factors influencing the ultrasonic fetal weight estimation [PDF]

, 2008
Objective: The aim of our study was the evaluation of sonographic fetal weight estimation taking into consideration 9 of the most important factors of influence on the precision of the estimation. Methods: We analyzed 820 singleton pregnancies from 22 to
Alexander Strauss, Barnhard Y, Baum JD, Ben-Aroya Z, Benacerraf BR, Blann DW, Blickstein I, Bottoms SF, Carolin Kü, Chauhan SP, Chuang L, Davis RO, Deter RL, Divon MY, Dudley NJ, Edwards A, Farrell T, Ferrero A, Field NT, Hadlock FP, Hadlock FP, Hellmeyer L, Hill LM, Honarvar M, Ivo Markus Heer, Jouannic JM, Kaaij MW, Luke B, Martin Dugas, Medchill MT, Merz E, Meyer WJ, Mills MD, Mongelli M, Mongelli M, Moore TR, Nadin Vö, Nzeh DA, O'Keeffe DF, Owen P, Patterson RM, Predanic M, Pressman EK, Rossavik IK, Scott F, Shamley KT, Shepard MJ, Smith GC, Snijders RJ, Spinnato JA, Susanne Mü, Toohey JS, Townsend RR, Valea FA, Warsof SL, Wong SF, Zador IE   +56 more
core   +1 more source

Fox - Fordyce Disease, a Case Report

Revista de la Facultad de Medicina Humana, 2020
Fox-Fordyce disease is a non-infectious, infrequent inflammatory dermatosis of apocrine glands, isolated by a pruritic papular rash that usually begins frequently at puberty, and which may involve vulva, armpit and perianal region.
Katherine Luisa Contreras Gala
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Characteristics Symptoms of Imminent Eclampsia: A case Referent Study from a Tertiary Hospital in Tanzania [PDF]

, 2012
\ud \ud Maternal mortality in developing coun- tries is unacceptably high with eclampsia being con- sistently among the top causes. As yet, primary pre- vention of this complication is not possible since causes of pre-eclampsia are largely unknown and ...
France, John, Muganyizi, Projestine S.
core  

Maternal cell-free DNA-based screening for fetal microdeletion and the importance of careful diagnostic follow-up. [PDF]

, 2015
BackgroundNoninvasive prenatal screening (NIPS) by next-generation sequencing of cell-free DNA (cfDNA) in maternal plasma is used to screen for common aneuploidies such as trisomy 21 in high risk pregnancies.
Chu, Tianjiao, Clemens, Michelle, Peters, David G, Rajkovic, Aleksandar, Saller, Devereux N, Yatsenko, Svetlana A   +5 more
core   +2 more sources

Calcified Sister Mary Joseph nodule as the presenting complaint of advanced low-grade serous ovarian cancer

Radiology Case Reports, 2020
A healthy 38-year-old woman presented with a hard umbilical mass that has been growing for a few months in duration with no other significant symptoms and signs.
Luhe Yang, MD, CM, Marilyn Kinloch, MD, FRCPC, Vickie Martin, MD, FRCPC, Farid Rashidi, MD FRCPC   +3 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Gabapentin for pain management after osmotic dilator insertion and prior to dilation and evacuation: A randomized controlled trial. [PDF]

, 2020
ObjectiveTo evaluate if gabapentin 600 mg reduces pain after osmotic dilator placement the day before a dilation and evacuation (D&E) procedure.Study designWe conducted a double-blind, placebo-controlled, randomized (stratified by vaginal parity ...
Chen, Melissa J, Creinin, Mitchell D, Hou, Melody Y, Matulich, Melissa C, Melo, Juliana, Schimmoeller, Natasha R   +5 more
core   +3 more sources