Results 121 to 130 of about 3,145,963 (201)
Annual Report - Marine Biological Laboratory, 1929
, 1930 Annual report of the Marine Biological Laboratory in Woods Hole. 1929.
Marine Biological Laboratory (Woods Hole MA)
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Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1989
, 1990 Annual report of the Marine Biological Laboratory in Woods Hole. 1989.
Marine Biological Laboratory (Woods Hole MA)
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The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Illinois Collections Preservation Network (ICPN) Logo
, 2011 Logo created for branding of the Illinois Collections Preservation NetworkMade available in DSpace on 2013-05-08T20:59:14Z (GMT). No. of bitstreams: 2 license.txt: 4923 bytes, checksum: 3568ab34bde24044ec8ea05b1192aa03 (MD5) ICPN.LOGO.JPG: 319557 bytes ...
Illinois Collections Preservation Network
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Molecular Oncology, EarlyView.Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1950
, 1951 Annual report of the Marine Biological Laboratory in Woods Hole. 1950.
Marine Biological Laboratory (Woods Hole MA)
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Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Annual Report - Marine Biological Laboratory, 1941
, 1942 Annual report of the Marine Biological Laboratory in Woods Hole. 1941.
Marine Biological Laboratory (Woods Hole MA)
core
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source