Results 151 to 160 of about 196,995 (268)

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Multimodal imaging and molecular analysis of a 350-year-old purple heron mummy. [PDF]

Sci Rep
Lackner M, Zelger B, Schirmer M, Unterberger SH, Pallua AK, Schäfer G, Sieß M, Brosch I, Zelger B, Degenhart G, Hermann M, Arora R, Klosterhuber M, Parson W, Kustatscher E, Huck CW, Pallua JD.   +16 more
europepmc   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

PRESERVATION OF DILIETHAZEM IN BIOLOGICAL MATERIAL

Journal of Volgograd State Medical University, 2019
V.K. Shormanov, L.L. Kvachakhiia, D.P. Shcherbakov   +2 more
openaire   +1 more source

Anterior Cruciate Ligament Reconstruction Using Tibial Attachment - Preserving Hamstring Grafts: Early Clinical and Magnetic Resonance Imaging Assessment of Graft Ligamentization. [PDF]

J Orthop Case Rep
Kawoosa AA, Mohi-Ud-Din A, Qadri WK, Jehangir M, Khan K.   +4 more
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Ethics of non-oncological fertility preservation from the perspective of the four principles of bioethics. [PDF]

Front Reprod Health
Aleksandrova-Yankulovska S, Orzechowski M, Hancke K, Bundschu K, Steger F.   +4 more
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Guided Alveolar Ridge Preservation (G-ARP) with a Subperiosteal Cortical Lamina: A Retrospective Observational Case Series. [PDF]

Dent J (Basel)
Guerra Cobian O, Mainetti G, Bengazi F, Mainetti T, Apaza Alccayhuaman KA, Nonaka M, Botticelli D.   +6 more
europepmc   +1 more source