Results 91 to 100 of about 1,171,113 (289)

Maximum principle for the finite element solution of time dependent anisotropic diffusion problems

open access: yes, 2013
Preservation of the maximum principle is studied for the combination of the linear finite element method in space and the $\theta$-method in time for solving time dependent anisotropic diffusion problems. It is shown that the numerical solution satisfies
Huang, Weizhang, Li, Xianping
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Inequality Preserving Rationing [PDF]

open access: yes
The present paper considers rationing problems interpreted as e.g. bankruptcy problems or taxation problems. We demonstrate that among the continuous and order-preserving rationing methods, theproportional method is the only rationing method that ...
Jens Leth Hougaard, Lars Peter Østerdal
core  

Power and Practice in Academic Library Materials Selection Paradigms [PDF]

open access: yes, 2011
This article examines the theoretical and practical implications of three methods of materials acquisitions in an academic library. First, it evaluates how traditional collection development, electronic patron driven acquisitions (PDA) and other older ...
Smith, Elena S
core   +2 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Research On A Novel Method For VRF Tooth Preservation

open access: yesInternational Dental Journal
Aim or purpose: Propose a novel therapeutic approach for verticall root fractured (VRF)tooth preservation, with fracture resistance evaluation via Finite element analysis(FEA) and ex vivo mechanical testing. Materials and methods: 1.
Chen Yiting, Zhang Haiying, Hou Benxiang
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Digital preservation practices in academic libraries in South Africa in the wake of the digital revolution

open access: yesSouth African Journal of Information Management, 2019
Background: The preservation of digital resources in academic institutions in South Africa is an imperative because of the proliferation of digital resources and the realities of the digital revolution. The study focused on digital preservation practices
Tlou M. Masenya, Patrick Ngulube
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

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