Results 51 to 60 of about 310,989 (265)
Modern methods of fixation of biological material for educational purposes
Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровьеTo ensure the safety of the educational process, the world is constantly looking for new ways to fix autopsy material. The purpose of our work was to search for literature data on new preservative solutions used in modern conditions for the fixation of ...
К. N. Krupin +4 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Shipin gongye ke-jiTricholoma matsutake was known for its high value. However, it was essential to maintain the quality of Tricholoma matsutake and extend its storage period due to its seasonality, difficulty in harvesting and short shelf life.
Hongwei YAO +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Top web preservation programs’ solutions in facing technical challenges [PDF]
تحقیقات کتابداری و اطلاعرسانی دانشگاهی, 2014 Objective: The present study aims to verify web preservation projects and programs in order to explore their preferred solutions in tackling the technical challenges.
Hajar Sotudeh, kianoosh Rashidi
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Comparison of the Preservation Effects of Entomogenous Fungi with Glycerin, Sand Tube and PDA Slant
Guangdong nongye kexue【Objective】Entomogenous fungi are susceptible to strain degradation and reduced activity during the passage process. Selection of suitable strain preservation methods is a critical measure to reduce the passage of fungal culture in laboratory.【Method ...
Fengting HE +5 more
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source