Results 111 to 120 of about 7,510,132 (348)

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

open access: yesMolecular Oncology, Volume 19, Issue 5, Page 1347-1370, May 2025.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar   +4 more
wiley   +1 more source

Sharp constants for composition with a bi-Lipschitz measure-preserving map [PDF]

open access: yesarXiv, 2012
In this note, we aim to describe sharp constants for the composition operator with a bi-Lipschitz measure-preserving map in several functional spaces (BMO, Hardy space, Carleson measures, ...). It is interesting to see how the measure preserving property allows us to improve these constants. Moreover, we will prove the optimality of our results for the
arxiv  

How to better select SARS-CoV-2 preservation solution of virus nucleic acid testing. [PDF]

open access: yesJ Clin Lab Anal, 2023
Duan X   +7 more
europepmc   +1 more source

Towards a Privacy-Preserving Solution for OSNs [PDF]

open access: yes, 2013
In this short paper, we describe a solution to protect users’ privacy in online social networks (OSNs). The solution achieves the following functionalities: (1) it enables users to store their private data securely; (2) it enables users, from the same or different OSNs, to compute their similarity through a secure protocol; (3) it enables similar users
openaire   +3 more sources

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

Construction of positivity preserving numerical schemes for multidimensional stochastic differential equations [PDF]

open access: yesarXiv, 2013
In this note we work on the construction of positive preserving numerical schemes for systems of stochastic differential equations. We use the semi discrete idea that we have proposed before proposing now a numerical scheme that preserves positivity on multidimensional stochastic differential equations converging strongly in the mean square sense to ...
arxiv  

CRISPR targeting of FOXL2 c.402C>G mutation reduces malignant phenotype in granulosa tumor cells and identifies anti‐tumoral compounds

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1092-1116, April 2025.
FOXL2 c.402C>G mutation drives granulosa cell tumors. Using CRISPR technology, we selectively corrected this mutation, reducing malignancy and increasing sensitivity to dasatinib and ketoconazole. Transcriptomic changes revealed potential therapeutic targets, demonstrating CRISPR's promise for treating this rare ovarian cancer.
Sandra Amarilla‐Quintana   +17 more
wiley   +1 more source

Effect of PERLA®, a new cold-storage solution, on oxidative stress injury and early graft function in rat kidney transplantation model

open access: yesBMC Nephrology
Background The composition of organ preservation solutions is crucial for maintaining graft integrity and early graft function after transplantation.
Mohamed Bejaoui   +3 more
doaj   +1 more source

Splenic implant preservation after conservation in lactated Ringer´s solution

open access: yesRevista do Colégio Brasileiro de Cirurgiões, 2018
Objective: to evaluate the morphology and function of autogenous splenic tissue implanted in the greater omentum, 24 hours after storage in Ringer-lactate solution. Methods: we divided 35 male rats into seven groups (n=5): Group 1: no splenectomy; Group
ARGOS SOARES DE MATOS FILHO   +3 more
doaj   +1 more source

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