Results 71 to 80 of about 8,103,935 (333)
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
FEBS Letters, EarlyView.Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
Towards a framework for predicting whole life-cycle cost for long-term digital preservation [PDF]
, 2013 Estimating the costs for the whole lifecycle of long-term digital preservation (LTDP) activities ena-bles decision makers to choose carefully what data to preserve, duration of preservation and type of preservation techniques best applied for their ...
Badawy, Mohamed +3 more
core
Plastic and Reconstructive Surgery, Global Open, 2022 Background:. Static cold storage is the gold standard of preservation in vascularized composite allotransplantation and allows a preservation time of 4–6 hours. Machine preservation is a promising technique for prolonged preservation; however, studies on
Kaj Brouwers, MD +7 more
doaj +1 more source
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
A classification of volume preserving generating forms in R^3 [PDF]
Discrete and Continuous Dynamical Systems - Series A 36.4, pp.
2285-2303 (2016), 2014 In earlier work, Lomeli and Meiss used a generalization of the symplectic approach to study volume preserving generating differential forms. In particular, for the $\mathbb{R}^3$ case, the first to differ from the symplectic case, they derived thirty-six one-forms that generate exact volume preserving maps.
arxiv +1 more source
Preservation solution supplemented with biliverdin prevents lung cold ischaemia/reperfusion injury.
European Journal of Cardio-Thoracic Surgery, 2012 OBJECTIVES Biliverdin (BV), one of the byproducts of heme catalysis through the heme oxygenase system, is a known scavenger of the reactive oxygen species.
R. Sugimoto +7 more
semanticscholar +1 more source
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Hyperbranched polyglycerol as a colloid in cold organ preservation solutions.
PLoS ONE, 2015 Hydroxyethyl starch (HES) is a common colloid in organ preservation solutions, such as in University of Wisconsin (UW) solution, for preventing graft interstitial edema and cell swelling during cold preservation of donor organs.
Sihai Gao +6 more
doaj +1 more source
SAGE Open Medicine, 2021 Vascularized composite allotransplantation represents the final level of the reconstructive ladder, offering treatment options for severe tissue loss and functional deficiencies.
Shaishav Datta +2 more
doaj +1 more source