Results 231 to 240 of about 556,859 (308)

Qualitative and quantitative assessment of related substances for ketoconazole cream based on national drug sampling inspection in China. [PDF]

BMC Chem
Xin C, Xun Y, Zhou Y, Wang F, Li F, Wu Q, Wu P, Ding D, Liu L, Zhao L, Yang L.   +10 more
europepmc   +1 more source

Mucoadhesive Peptide‐Catalase Self‐Assembled Nano‐Formulation for Effective Treatment of Mucosal Inflammatory Diseases

Advanced Science, EarlyView.
CR8L10 is self‐assembled with catalase (CAT) to form CR8L10@CAT nanocomplexes, which can anchor to mucosal surfaces via thiol‐disulfide exchange with mucin, thereby enhancing their mucosal retention. The efficient reactive oxygen species (ROS) scavenging at inflamed sites would then result in successful treatment in both the intravesical IC/BPS model ...
Xinzhu Li, Yuxuan Ma, Di He, Yingying Huang, Yutong Jiang, He Zhao, Shengjie Ge, Ruirui Zhao, Hejia Yuan, Wendi Jiang, Wenjun Zhu, Kai Liu, Han Zhang, Zhuang Liu   +13 more
wiley   +1 more source

Potential side effects of toxic and restricted substances found in cosmetics declared to be of natural origin. [PDF]

Front Public Health
Koncz D, Nemeth MA, Pallagi E, Tóth B, Csupor D.   +4 more
europepmc   +1 more source

Oral Prebiotic Polysaccharide Hydrogels Sustaining Colon Antibody Release Alleviate Inflammatory Bowel Disease

Advanced Science, EarlyView.
An orally administered prebiotic polysaccharide hydrogel (predaGel) based on inulin and alginate‐dopamine is stable in the stomach, adheres to the intestine, and degrades slowly in the colon. It enables site‐specific delivery of anti‐TNF‐α and anti‐IL‐12/23 antibodies, scavenges reactive oxygen species, and remodels gut microbiota, offering effective ...
Xinyi Dong, Huan He, Li Cao, Fenghua Meng, Zhiyuan Zhong   +4 more
wiley   +1 more source

Excipients in pharmaceuticals: mechanisms of hypersensitivity and the role of global pharmacovigilance. [PDF]

Saudi Pharm J
Malkawi R, Altahrawi L.
europepmc   +1 more source

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

Advanced Science, EarlyView.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai, Rhonda Kelley, Ying Lao, M. Immanuel Reyes Madlangsakay, Prasanta Paul, M. Alejandra Llanes‐Cuesta, Jun‐Feng Wang, René P. Zahedi, Jiming Kong, Geoffrey K. Tranmer   +9 more
wiley   +1 more source

Development and Physicochemical Characterisation of Probiotic Emulsions Containing <i>Lactobacillus rhamnosus</i> for Potential Dermal Applications. [PDF]

Pharmaceutics
Gasztych M, Dudek-Wicher R, Brzozowski D, Dołowacka-Jóźwiak A, Musiał W.   +4 more
europepmc   +1 more source

Paternal Sperm Gnas‐ICR Epigenetic Programming Contributes to PPP‐Like Phenotypes in Female Offspring

Advanced Science, EarlyView.
A paternal glucocorticoid–sperm Gnas‐ICR axis is linked to ovarian endocrine programming in female offspring. Paternal preconception caffeine exposure elevates corticosterone, promotes sperm Gnas‐ICR hypermethylation, and is associated with ovarian Gnas upregulation, cAMP/PKA/CREB–StAR activation, enhanced estradiol synthesis, and PPP‐like phenotypes ...
Jing Huang, Lu Chen, Tiancheng Wu, Yating Li, Hui Wang   +4 more
wiley   +1 more source

Comparative Assessment of Antibacterial Activity of Haskap Berry (Lonicera caerulea L.) Extract, Gallic Acid, and Combination Against Alicyclobacillus acidoterrestris for Application in Orange Juice. [PDF]

J Food Sci
Qi F, Liu J, Xu T, Meng J, Ren M, He M, Liu Y, Shi Y.   +7 more
europepmc   +1 more source

Calcium‐Mechanochemistry Enabled Ketone Synthesis From Organic Iodides and Carboxylic Acids

Advanced Science, EarlyView.
Mechanochemically generated organocalcium species display unusual chemoselectivity toward carboxylates, enabling direct ketone synthesis without overaddition. Ball milling activates commercial calcium metal under ambient, solvent‐minimized conditions, providing a broad substrate scope, high functional‐group tolerance, and a practical one‐step ...
Mengyao Pei, Zekun Yang, Xueyan Yang, Yufang Yang, Yangyang Shen, Jiemin Wang, Peile Ma, Zezhu Li, Xiaoliang Zheng, Xiaofeng Wei   +9 more
wiley   +1 more source