Results 241 to 250 of about 9,300 (298)
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Preservatives in Pharmaceuticals: Are They Really Safe?
Current Drug Safety, 2023Abstract: Preservatives are the ingredients that are utilized in order to improve the shelf life of products (Medicines, food). These tend to slow down or stop the degradation or decomposition processes, therefore, enhance the shelf life of the products.
Mohit Kumar +3 more
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Preservatives in liquid pharmaceutical preparations
Drug Testing and Analysis, 2009Sodium benzoate, potassium sorbate, and methyl hydroxybenzoate are commonly used as preservatives in liquid pharmaceutical preparations. The purpose of this study is to determine the amount of the aforementioned preservatives in pharmaceutical products, as some recent studies have reported serious side effects associated with the ingestion of these ...
Chawki Boukarim +4 more
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The chemistry of lysozyme and its use as a food preservative and a pharmaceutical
C R C Critical Reviews in Food Science and Nutrition, 1988The chemistry and use of lysozyme as a food preservative and a pharmaceutical are reviewed. Lysozyme inhibits the growth of deleterious organisms, thus prolonging shelf life. Chemicals used to improve the preservative effect of lysozyme and those that inhibit the enzyme are discussed, along with the stability of lysozyme in various chemical ...
Valerie A. Proctor +2 more
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Challenge testing — the laboratory evaluation of the preservation of pharmaceutical preparations
Antonie van Leeuwenhoek, 1981The need for adequate preservation and the difficulties of definition and testing are outlined and pharmacopoeial challenge tests are compared. While similar in principle they differ in detail and in the interpretation of results. The USP test is intended for multi-dose sterile products but BP and draft EP tests include also criteria for topical and ...
D. F. Spooner, B. Croshaw
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PHARMACEUTICAL AIDS: ORGANOLEPTIC AGENTS AND PRESERVATIVES IN INDIA
2023This chapter delves into pharmaceutical aids, focusing on organoleptic agents (colouring, flavouring, sweetening) and preservatives. Organoleptic agents, crucial for sensory characteristics, enhance patient acceptance and mask unpleasant drug attributes.
Mr. Mohd Asif, Ms. Shelly Raghav
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Evaluating preservative efficacy in pharmaceutical and cosmetic products
2022In 1965 the Royal Swedish Medical Board reported high levels of microbial contamination in nan-sterile drug products not normally required to be sterile (Kallings and Enerfeldt, 1965], Since then a number of surveys have confirmed these findings in both pharmaceutical and cosmetic products e.g. Schiller et.al.
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Determining the efficacy of preservatives in pharmaccutical products
Journal of the American Pharmaceutical Association (Scientific ed.), 1955A standardized method of testing the efficacy of preservatives in pharmaceutical products is presented. The test consists of the addition of a predetermined number of microorganisms of different species to the product, incubation of the contaminated test material, and sampling at fixed time intervals to determine whether growth of the organisms occurs ...
E J, RDZOK +3 more
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Halogen Bonding and Pharmaceutical Cocrystals: The Case of a Widely Used Preservative
Molecular Pharmaceutics, 20133-Iodo-2-propynyl-N-butylcarbamate (IPBC) is an iodinated antimicrobial product used globally as a preservative, fungicide, and algaecide. IPBC is difficult to obtain in pure form as well as to handle in industrial products because it tends to be sticky and clumpy. Here, we describe the preparation of four pharmaceutical cocrystals involving IPBC.
BALDRIGHI, MICHELE +7 more
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Preservative Efficacy Screening of Pharmaceutical Formulations Using ATP Bioluminescence
Drug Development and Industrial Pharmacy, 2008The preservative challenge test is a method used to determine the efficacy of a preservation system in a pharmaceutical or cosmetic formulation. However, such testing is a labor-intensive, repetitive task often requiring days before results can be generated. Several alternatives to traditional colony-count techniques have been developed.
Mateja, Kramer +2 more
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Storage of natural water samples and preservation techniques for pharmaceutical quantification
Talanta, 2013In order to perform a human and ecological risk assessment of pharmaceutical products (PPs) in natural waters, it is necessary to accurately quantify a broad variety of PPs at low concentrations. Although numerous currently implemented analytical methodologies, less is known about the preservation of PPs in natural water samples within the period ...
Mompelat, S. +3 more
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