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Preservatives in Pharmaceuticals: Are They Really Safe?

Current Drug Safety, 2023
Abstract: Preservatives are the ingredients that are utilized in order to improve the shelf life of products (Medicines, food). These tend to slow down or stop the degradation or decomposition processes, therefore, enhance the shelf life of the products.
Mohit Kumar   +3 more
openaire   +2 more sources

Preservatives in liquid pharmaceutical preparations

Drug Testing and Analysis, 2009
Sodium benzoate, potassium sorbate, and methyl hydroxybenzoate are commonly used as preservatives in liquid pharmaceutical preparations. The purpose of this study is to determine the amount of the aforementioned preservatives in pharmaceutical products, as some recent studies have reported serious side effects associated with the ingestion of these ...
Chawki Boukarim   +4 more
openaire   +1 more source

The chemistry of lysozyme and its use as a food preservative and a pharmaceutical

C R C Critical Reviews in Food Science and Nutrition, 1988
The chemistry and use of lysozyme as a food preservative and a pharmaceutical are reviewed. Lysozyme inhibits the growth of deleterious organisms, thus prolonging shelf life. Chemicals used to improve the preservative effect of lysozyme and those that inhibit the enzyme are discussed, along with the stability of lysozyme in various chemical ...
Valerie A. Proctor   +2 more
openaire   +2 more sources

Challenge testing — the laboratory evaluation of the preservation of pharmaceutical preparations

Antonie van Leeuwenhoek, 1981
The need for adequate preservation and the difficulties of definition and testing are outlined and pharmacopoeial challenge tests are compared. While similar in principle they differ in detail and in the interpretation of results. The USP test is intended for multi-dose sterile products but BP and draft EP tests include also criteria for topical and ...
D. F. Spooner, B. Croshaw
openaire   +1 more source

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